摘要
目的观察还原型谷光甘肽(GSH)对慢性病毒性肝炎的疗效,为进一步应用GSH治疗病毒性肝炎及护理提供科学依据。方法将120例患者分为试验组和对照组,分别采用GSH和异甘草酸镁治疗。结果试验组与对照组总有效率均达到90.0%,两组病毒性肝炎治疗效果差异无统计学意义;用还原型谷胱甘肽治疗和异甘草酸镁治疗前后肝功能各指标均明显改善(P<0.05或P<0.01)。结论 GSH是治疗病毒性肝炎安全有效的药物,病毒性肝炎患者还应防治继发性感染,注意观察有无腹膜炎、肺炎、尿路感染等。
OBJECTIVE To evaluate the effects of reduced glutathione treatment for viral hepatitis and provide a scientific basis for the further clinical application.METHODS A total of 120 cases of viral hepatitis patients were randomly divided into two groups as experimental group and control group,and treated with reduced glutathione（GSH） and magnesium isoglycyrrhizinate respectively.RESULTS Effective rate of both experimental group and control group reached 90.0%,and there’s no statistical significance between the two groups（P〉0.05）.Liver function indexes were significantly improved after treatment by using reduced glutathione（P〈0.05） and magnesium isoglycyrrhizinate（P〈0.01）.CONCLUSION Reduced glutathione（GSH） is a safe and effective drug for the treatment of viral hepatitis.Viral hepatitis patients also should pay attention to the observation of peritonitis,pneumonia,urinary tract infection and other signs in order to prevent secondary infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第17期3788-3789,共2页
Chinese Journal of Nosocomiology
