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葡萄糖酸锌治疗小儿轮状病毒腹泻的有效性及安全性分析 被引量:12

葡萄糖酸锌治疗小儿轮状病毒腹泻的有效性及安全性分析
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摘要 目的探讨葡萄糖酸锌治疗小儿轮状病毒腹泻的临床疗效及安全性。方法本研究按照随机数字表法将186例轮状病毒腹泻患儿随机分为研究组和对照组,其中,对照组患儿给予补液纠正脱水、维持水电解质平衡,对症给予妈咪爱、思密达治疗。研究组患儿则在上述常规治疗的基础上给予葡萄糖酸锌口服。结果研究组患儿腹泻停止时间较对照组患儿明显缩短(P<0.05)。研究组的总有效率明显高于对照组(P<0.05)。两组患儿均未发生不良反应。结论葡萄糖酸锌治疗小儿轮状病毒腹泻临床疗效确切,无明显不良反应,易被家长接受,值得临床推广使用。 Objective To investigate the efficacy and safety analysis of Zinc gluconate in treatment of children with rotavirus diarrhea. Methods The study in accordance with the random number table, 186 cases of rotavirus diarrhea were randomly divided into study group and control group, in which the control group were given rehydration to correct dehydration, maintain fluid and electrolyte balance, give mamiai and simida. The study group children were given zinc gluconate on the basis of the above conventional treatment. Results The antidiarrheal time of the study group was shorter than the control group (P〈0.05). The total efficiency of the study group was significantly higher than the control group (P〈0.05). The two groups of children didn't have adverse reactions. Conclusion Zinc gluconate treatment of children with rotavirus diarrhea, clinical efficacy is exactly, no significant adverse reactions, susceptible parents to accept. It is worthy of clinical use.
出处 《当代医学》 2012年第27期144-145,共2页 Contemporary Medicine
关键词 葡萄糖酸锌 轮状病毒 腹泻 疗效 安全性 Zinc gluconate Rotavirus Diarrhea Efficacy Security
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