1Wong BC,Jiang X,Fan XM,et al.Suppression on Rel A/P65nuclear translocation independent of Ikappa-alpha degradation by cycloo-xygenase-2inhibitor in gastric cancer[J].Oncogene,2003,22(8):1189-1197.
2Sasaki N,Morisaki T,Hashizume K,et al.Nuclear factor kappa Bp65(RelA)transcription factor is constitutively activated in human gastric carcinoma tissue[J].Clin Cancer,2001,7(12):4136-4142.
3Biswas SK,McClure D,Jimenez LA,et al.Curcumln induces glutathione blosynthesis and inhibits NF-kB activation and interleukin-8release in alveolar ePithelial cells.Mechanism of free radlcal scavenging activity[J].Antloxd Redox Slgnal,2005,7(1-2):32-41.
5Ji H,Wang Z,Perera SA,et al.Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models[J].Cancer Res,2007,67(10):4933-4939.
6Vicent S,Garayoa M,Lopez-Picazo JM,et al.Mitogen-activated protein kinase phosphatase-1is overexpressed in non-small cell lung cancer and is an independent predictor of outcome inpatients[J].Clin Cancer RES,2004,10(11):3639-3649.
7de Melo M,Gerbase MW,Curran J,et al.Phosphorylated extrace-llular signal-regulated kinases are significantly increased in malignant mesothelioma[J].J Histochem Cytochem,2006,54(8):855-861.
3GRADHAKRISHNAPILLAI,ANANDSSRIVASTAVA,TAREKJ HASSANEIN, et al. Induction of apoptosis in human lung cancer cells by curcumin[J]. Cancer Lett,208(2004) : 163-170.
4KUO ML, HANG TS, LIN JK. Curcumin,an antioxidant and antitumor promoter ,induces apoptosis in human leukemia ceils [J]. Biochim Biophys Acta, 1996,1317 ( 2 ) : 95.
5LI F, AMBROSINI G, CHU EY, et al.Control of apoptosis and mitotic spindle checkpoint by surviving[J].Nature, 1998,396 (6711 ) : 580- 584.
6BUSH JA,CHEUNG KJ,LI GANG,et al. Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53 [ J ]. Exp Cell Res, 2001,271 (2) : 305-314.
7AMBROSINI G,ADIDA C,SIRUGO G,et al.Induction of apoptosis and inhibition of cell proliferation by surviving gene targeting [J]. J Biol Chem, 1998,273(18) : 11177-11182.
8Kawasaki H, Altieri DC, Lu CD, et al. Inhibition of apoptosis by Survivin predicts shorter survival rates in colorectal cancer. Cancer Res, 1998 ,Nov 15 ;58(22) :5071 -4.
9Ambrosini G, Adida C, Altieri DC, et al. A novel anti-apoptosis gene Survivin, expressed in cancer and lymphoma. Nat Med, 1997,3:917 -21.
10Akyurek N, Mends L, Ekinci O, et al. Survivin expression in preinvasive lesions and non-small cell lung carcinoma. Virchows Arch, 2006, 449(2) : 164 - 170.
4Enari M, Sakahira H,Yokoyama H, et al. A caspase-ac-tivated DNase that degrades DNA during apoptosis, andits inhibitor ICAD[J]. Nature, 1998, 391(6662); 43-50.
5Sakahira H,Enari M,Nagata S.Cleavage of CAD in-hibitor in CAD activation and DNA degradation dur-ing apoptosis [J].Nature, 1998,391(6662):96-99.
6Berridge MJ, Bootman MD,Lipp P. Calcium-a life anddeath signal [J]. Nature, 1998,395 (6703): 645-648.
7Verhagen AM,Eckert PG,Paunch M, et al.Identifica-tion of DIABLO, mammalian protein that promotes ap-optosis by binding to and antagonizing IAP proteins[J].Cell,2000,102 (1):43-53.
8Sutherland LC,Wang K,Robinson AG. RBM5 as a putativetumor suppressor gene for lung cancer [J]. Jou malof Thoracic Oncology,2010,5 (3):294-298.
9Ramaswamy S,Ross KN,Lander ES,et al. A molecularsignature of metastasis in primary sol id tumors[J].Nat Genet,2003,33(1):49-54.
10Oh JJ,Razfar A. ,Delgado I,et al. 3p21. 3tumor sup-pressor gene h37/lucal5/RBM5 inhibits growth ofhuman lung cancer cells through cell cycle arrestand apoptosis [J].Cancer Res,2006,66 (7):3419-3427.