摘要
经皮冠状动脉介入治疗(PCI)后发生的无复流(NRF)严重影响患者的预后,而急性心肌梗死(AMI)患者PCI术后NRF的发生率可高达10%～30%。尽管NRF的防治方法众多,但临床疗效欠佳。已有的临床研究表明,长期接受他汀类药物治疗和术前7d短期的他汀类药物强化治疗,均可以降低AMI患者PCI术后NRF的发生,这为预防PCI术后心肌NRF开辟了一条新途径。
No-reflow（NRF）phenomenon after percutaneous coronary intervention（PCI）seriously affects the patient’s prognosis.The incidence of NRF in patients with acute myocardial infarction treated with PCI is up to 10%-30%.Despite the numerous methods of prevention and treatment of NRF,the clinical efficacy is poor.Existing clinical studies have shown that long-term statin therapy and preoperative seven days of short-term statin intensive treatment can reduce the occurrence of NRF.It will provide a new way for the prevention of NRF after PCI.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2012年第9期641-642,共2页
Journal of Clinical Cardiology
关键词
冠心病
他汀
无复流
介入治疗
coronary disease
statins
no-reflow
percutaneous coronary intervention
