摘要
目的探讨激光氧液加东莨菪碱(laser oxygenate fluid and scopolamine,LOFS)辅助治疗儿童难治性癫痫的疗效及护理。方法回顾性分析2005年1月至2009年12月解放军第97医院儿科收治的1～14岁难治性癫痫患儿68例的临床资料。所有患儿在原有的抗癫痫药物治疗基础上,采用DJF-IA型多功能激光血液治疗仪,以5%葡萄糖5～10ml/kg做载体,置于血疗仪中,接受He-Ne激光照射15min并充氧,加用东莨菪碱0.01～0.03mg/kg,静脉滴注1次/d,疗程为10d/月,连续3个疗程。结果激光氧液加东莨菪碱辅助治疗前3个月内,68例患儿各类型癫痫发作总频次为34 792次/月,平均(659±31.24)次/月;LOFS治疗3个月过程中,发作总频度为965次/月,平均(14±5.36)次/月,减少了89.99%,总有效率为95.59%。各类型癫痫患儿发作明显减少,有较好的近期疗效。结论 LOFS辅助治疗难治性癫痫患儿疗效良好,无明显不良反应。密切观察患儿发作症状,正确氧疗及护理可有效保证治疗的效果。
Objective To explore the effect and nursing strategy of the laser oxygenate fluid and scopolamine （LOFS） for children with refractory epilepsy. Methods The clinical data of 68 children with intractable epilepsy,aged 1-14 years, undergoing LOFS treatment from January 2005 to December 2009 were analyzed retrospectively. In addition to the intrinsical antiepilepsy drugs, LOFS were prepared by the DJF-IA-based multi-function laser blood treatment device, with 5 % glucose （5-10 ml/kg）carrier in the blood treatment apparatus, under the exposure to He-Ne laser irradiation for 15min and oxygenation,followed by scopolamine （0.01-0.03 mg/kg）. LOFS was administrated by intravenous infusion once a day for 10 days per month for consecutive three months. Results The overall frequency of seizures with various seizure types during three months before LOFS treatment was 34,792 times/month, （mean 659 ± 31.24 times/month）. During the three months of LOFS treatment,the total frequency of various seizures descended to 965 times/month （89.99;）（mean 14±5.36 times/month） and the total efficiency was 95.59%. LOFS treatment had a significant short-term effect in reducing the incidences of various types of seizures in children. Conclusion LOFS is a new effective auxiliary therapy for intractable epilepsy, without significant adverse reactions. Close observation of the seizure symptoms, proper oxidation and nursing are all contribute to greater therapeutic effect.
出处
《解放军护理杂志》
2012年第18期13-15,共3页
Nursing Journal of Chinese People's Liberation Army
基金
南京军区医学科技创新课题(2009MB119)
关键词
激光氧液
东莨菪碱
难治性癫痫
添加治疗
护理
laser liquid oxygen plus scopolamine（LOFS）
intractable epilepsy
add-on treatment
nursing
