摘要
目的初步建立厦门地区健康成年女性血清CA125的参考值范围。方法用罗氏Elecsys2010全自动电化学发光免疫分析仪及CAl25测定原装配套试剂盒（电化学发光免疫测定法）对1191例成年健康女性的新鲜血清进行测定，测定结果按CLSIC28-A3（临床实验室参考范围的定义和确认，第3版）进行统计处理，确定健康女性CA125正常参考值范围。结果研究显示，CAl25检验数据呈偏态分布。该研究确定厦门地区健康女性CA125总体参考范围为〈26．52U／ml，与推荐参考值范围（35±0．7U／ml）的比较差异有统计学显著性意义（P〈0．001）。结论厦门地区成人健康女性CA125的95％参考范围低于推荐参考范围，调查确定的参考范围与推荐参考范围有差异。
Objective To establish the reference range of Cancer Antigen （CA125） for healthy female adults in Xiamen. Methods 1 191 serum samples of healthy female adults in Xiamen were collected and tested by Elecsys2010 Roche （electro- chemil immunoassay） and CA125 assay kit. After statistically analyzed according to CLSI C28- A3. （How to define and determine reference intervals in the clinical laboratory;approved guideline,3rd edition）. Results The total reference range of 95 percentiles of CA125 of healthy female adults in Xiamen were 〈26.52 U/ml. It was statistic difference from reagent kits （35±0. 7 U/ml） （P〈0. 001）. Conclusion The reference range of 95 percentiles of healthy female adults was lower than the used reference range from reagent kits, which should not be generally used.
出处
《现代检验医学杂志》
CAS
2012年第4期111-112,共2页
Journal of Modern Laboratory Medicine
