摘要
目的了解衡阳地区绿脓假单胞菌的临床分布特征及耐药现状,为临床合理使用抗菌药物提供依据。方法收集衡阳市南华大学附一医院临床分离的199株绿脓假单胞菌,采用K-B法检测药物敏感性。结果 199株绿脓假单胞菌中,以痰液为主,占64.32%(128/199);其次为伤口分泌物,占9.05%(18/199)。病区来源以ICU检出率最高,占14.07%(28/199);其次为神经外科和呼吸内科,占9.05%(18/199)。在检测的19种药物中,耐药率超过50%的达13种(68.42%),耐药率最高为氨苄西林/舒巴坦(98.00%),其次为复方新诺明(95.00%)和替卡西林(79.00%),耐药率最低为多粘菌素E(8.00%)。结论临床分离绿脓假单胞菌多来源于呼吸道标本,且耐药现象十分严重。临床应加强对绿脓假单胞菌耐药性监测、合理选用抗菌药物。
Objective To analyzed the clinical distribution and commonly used drug resistance of 199 Pseudomonas aeruginosa in Hengyang district, to supply evidences for the clinical use of antibiotic therapy. Methods The KB method was used to detect the 18 kinds of antimicrobial drug resistance status of 199 clinical isolated Pseudomonas aeruginosa. Results Among 199 isolates, 64.32 % （ 128/199 ） came from sputum, 9.05 % （18/199） from tresis vulnus excreta. The most strains from intensive care unit, accounting for 14.07%（28/199）, 9.05% （ 18/199） from neurosurgery. In the 199 strains of Pseudomonas aeruginosa, 63 stains were multi - resistant. The lowest rate of drugresistance was Polymyxin E （8.00%）. The highest rate of drug - resistance was Ampicillin/sulbactam （98.00%）. Conclusion Clinical isolates of Acinetobacter baumannil came from the sputum, bronchial aspiration material and intensive care unit mainly and their resistant rates were rather high. More attention should be paid to the surveillance of antimicrobial resistance of Pseudomonas aeruginosa in clinics and prevent transmission and epidemic of their resistance strains.
出处
《湘南学院学报（医学版）》
2012年第3期31-33,共3页
Journal of Xiangnan University（Medical Sciences）
基金
衡阳市科学技术局科研项目(2009kj36)
关键词
绿脓假单胞菌
临床分布
耐药性
Acinetobacter baumanii
Clinical distribution
Drug resistance
