摘要
目的探讨Narcotrend麻醉/脑电意识深度监测系统在丙泊酚靶控输注(TCI)下对ICU机械通气患者镇静深度数字化监测的可行性。方法选取20例ICU呼吸机机械通气同时进行丙泊酚靶控输注镇静患者,应用Narcotrend进行监测。靶控浓度(Ct)从0.5ug/ml开始递增,达到满意镇静深度为止,观察NTI、Ramsay评分。结果丙泊酚滴定法靶控输注镇静时NTI随着Ct递增而递减,Ramsay评分随着Ct递增而递增,NTI与Ramsay呈负相关,相关系数r为-0.887;NTI与Ct呈负相关,相关系数r为-0.756;Ramsay评分与Ct呈正相关,相关系数r为0.735(P<0.01)。结论 Narcotrend在机械通气患者丙泊酚TCI镇静深度评估中具有较好的相关性和可控性,可以对丙泊酚TCI镇静实现数字化监测。
Objective To investigate the feasibility of using Narcotrend for digital monitoring the TCI of propofol for patients with mechanical ventilation in ICU. Methods Twenty patients with mechanical ventilation in ICU were enrolled in this study. Propofol was administered by Grasby 3500 TCI system. The target concentration （CO of propofol was increased step by step with 0.5 li g/ml as the initial concentration until satisfactory sedation was achieved. The Narcotrend index was recorded and Ramsay sedation score was measured each time we changed Ct of 15 minutes. Results Narcotrend index decreased and Ramsay increased as the target effect-site concentration （Ct） of propofol increased step by step. There was a significant correlation between Narcotrend index and Ramsay, Narco- trend index and Ct, Ramsay and Ct （P〈0.01）. Conclusion Narcotrend may be used for digital monitoring the TCI of propofol in patients with mechanical ventilation in ICU.
出处
《海南医学》
CAS
2012年第20期96-98,共3页
Hainan Medical Journal
