摘要
目的:比较研究鼻腔淋巴瘤调强放疗(IMRT)和半野照射对靶区及其周围危及器官受照剂量的差异。方法:随机选择8例鼻腔淋巴瘤患者,进行CT扫描、靶区和危及器官的勾画,用三维治疗计划系统进行调强和半野照射的计划设计,并对结果进行比较分析。结果:调强计划对靶区适形度优于半野照射,差异具有统计学意义(P<0.005)。IMRT比半野照射能更好地保护某些正常组织,减少眼球、脑干、垂体和颞颌关节等正常组织的照射剂量(P<0.05),而对晶体、视交叉和视神经等正常组织2种计划无显著差异(P>0.05)。结论:在鼻腔淋巴瘤放疗中,IMRT较半野照射技术在剂量学方面有一定的优越性。
Objective To compare the dosimetric differences of the planning target volume（PTV） and the organs at risk （OAR） for postoperative patients with nasal lymphoma on intensity-modulated radiotherapy（IMRT） and mono-isocenter irradiation. Methods Eight postoperative patients with nasal lymphoma were chosen randomly. The next steps were CT scan, PTV and OAR contouring. The treatment protocols were designed into mono-isocenter irradiation and IMRT by TPS. Finally, the dose distribution and DVH were compared. Results About the confoimability of PTV, IMRT showed a significantly superior dose distribution and the differences（P〈0.005） have statistical significance. As compared with mono- isocenter irratiation, IMPT could protect some normal tissues, the received dose（P〈0.05） of normal tissues were reduced including eyeball, brain stem, pituitary and temporomandibular joint, but with no obvious differences for crystal, optic chiasma and optic nerve（P〉0.05）. Conclusion In postoperative radiotherapy for nasal lymphoma, IMPT has more dosimetric advantages over mono-isocenter irradiation technique in radiotherapy.
出处
《医疗卫生装备》
CAS
2012年第8期73-75,共3页
Chinese Medical Equipment Journal
关键词
鼻腔淋巴瘤
调强放疗
半野照射
剂量体积直方图
受量分析
nasal lymphoma
intensity-modulated radiotherapy（IMRT）
mono-isocenter irradiation
dose-volume his- togram（DVH）
received dosage analysis
