摘要
目的：观察卡维地洛在慢性心力衰竭的治疗中的疗效。方法：将72例慢性心力衰竭患者随机分为对照组和观察组。对照组给予常规治疗（利尿剂、ACEI或ARB、洋地黄类、硝酸酯类等）；治疗组在对照组治疗基础上加用卡维地洛，起始剂量为3．125mg2次／天口服，2周后剂量加倍．最大剂量为25mg，2次／天，6个月后进行比较。结果：卡维地洛治疗组患者的心功能、左室射血分数（LVEF）、6分钟步行距离试验、再住院率与对照组相比，均有显著性差异（P〈0．05）。结论：在应用利尿剂、ACEI或ARB、和洋地黄类等治疗的基础上加用卡维地洛治疗慢性心力衰竭疗效明显，可改善心功能。
Objective To observe earvedilol in patients with chronic heart failure （CHF） in the treatment efficacy. Methods 72 eases of CHF patients were randomly divided into control group and treatment group. Control group was given basic treatment （ diuretics, ACEI Or ARB, digitalis, nitrates, etc. ） ; treatment group were treated based on the application of carvedilol, the starting dose of 3. 125mg, 2 times/day, orally, two weeks after the double dose, maximum dose of 25mg, 2 times / day, compared to 6 months. Results in patients treated with carvedilol heart function, left ventricular ejection fraction （LVEF）, 6 minute walk distance test , Rehospitalizatian rate, compared with the control group, there were significant differences （ p 〈0.05 ） . Conclusions CHF patients with diuretics, ACEI or ARB and digitalis therapy based on the use of carvedilol can achieve better results.
出处
《成都医学院学报》
CAS
2012年第02Z期182-183,共2页
Journal of Chengdu Medical College
