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Dishevelled:WNT信号通路的关键蛋白 被引量:4

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摘要 Dishevelled(Dvl/Dsh)是Wnt信号通路上的关键蛋白,能将Wnt信号从受体传递到下游的效应因子上。经典Wnt信号通路中,Dvl被受体Fizzled召集到细胞膜上,与axin/GSK3/APC复合体结合,从而抑制细胞质内β-catenin的降解。本文对DVL在Wnt信号通路中的作用及作用的分子机制进行讨论。
作者 李宁 李建远
机构地区 烟台毓璜顶医院
出处 《中外医学研究》 2012年第28期148-149,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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参考文献19

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同被引文献41

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