摘要
目的:评估消化性溃疡患者治疗前后血清IL-2、IL-18和胃泌素水平的变化及临床意义。方法:应用放射免疫分析对38例消化性溃疡患者进行了治疗前后血清IL-2、IL-18和胃泌素水平测定,并与35名正常健康人作比较。结果:消化性溃疡患者在治疗前血清IL-2水平非常显著地低于正常人组(P<0.01),而血清IL-18、胃泌素水平又非常显著地高于正常人组(P<0.01),经治疗3个月后则与正常人组比较无显著性差异(P>0.05)。结论:检测消化性溃疡患者血清IL-2、IL-18和胃泌素水平的变化与疾病的进程密切相关,可确认具有提示预后的价值。
Objective To evaluate the clinical significance of changes on serum IL-2,IL-18 and gastrin levels in patients with peptic ulcer.Methods Serum IL-2,IL-18 and gastrin（with RIA）levels were determined in 38 patients with peptic ulcer both before and after treatment as well as in 35 normal controls.Results Before treatment,the serum IL-2 level was significantly lower in the patients with peptic ulcer than that in controls（P0.05）.Conclusion Serum IL-2,IL-18and gastrin levels were closely related to the diseases process of peptic ulcer and recognized to be of prognostic values.
出处
《放射免疫学杂志》
CAS
2012年第5期492-494,共3页
Journal of Radioimmanology
