摘要
目的比较恩度单用与恩度联合化疗治疗恶性胸腔积液的疗效。方法选取56例恶性胸腔积液患者,随机分为恩度单用组28例,恩度联合化疗组28例,分别进行治疗,评价两组患者的治疗效果、生活质量改善情况及不良反应发生情况。结果两组患者均完成1疗程化疗,其中联合组总有效率显著高于单药组,差异有统计学意义(P<0.05);两组患者不良反应均轻微,联合组的生活质量改善率明显高于单药组,差异有统计学意义(P<0.05)。结论恩度胸腔灌注化疗治疗恶性胸腔积液是一种安全有效的治疗方法,近期疗效满意,不良反应轻微,其联合顺铂用药疗效较单药更显著,值得进一步研究。
Objective To compare the clinical effect of endostar and endostar combined with chemotherapy on the treatment of malignant pleural effusion.Methods Randomly divided 56 cases of malignant pleural effusion to 2 groups： the endostar group and the endostar combined with chemotherapy group（the combined group）.And the patients were given treatment separately.The clinical effect,the life quality improvement and the side-effects were observed.Results After 1 course of treatment of endostar combined with chemotherapy,there was significant difference in the clinical effect and in the life quality improvement between the combined group with the endostar group（P 〈 0.05）.There were slight reactions in the two groups in the side-effects.Conclusion It is a safe and effective way for malignant pleural effusion with the treatment of endostar and chemotherapy and it can receive satisfactory recent effect and low side-effects.It is worth for further research.
出处
《中国医药科学》
2012年第15期52-53,共2页
China Medicine And Pharmacy
关键词
恩度
恶性胸腔积液
化疗
Endostar
Malignant pleural effusion
Chemotherapy
Clinical observation
