摘要
目的:探讨无痛纤支镜给药治疗空洞型肺结核的护理方法,探索空洞型肺结核短程化疗实施路径。方法:采用随机配对分组法,将126例空洞型肺结核患者分为治疗组(M组,63例)和对照组(C组,63例)。化疗方案:M组3HRZEAK/6HRE,另通过无痛纤支镜给药,强化期每周1次;C组不用纤支镜给药,化疗方案同M组。结果:强化期结束时,M组与C组痰菌阴转率分别为92.06%和49.21%,2组之间的差异具有统计学意义(χ2=27.894,P<0.01);空洞闭合率分别为67.67%和30.16%,2组之间的差异具有统计学意义(χ2=16.811,P<0.01)。疗程结束时,M组与C组痰菌阴转率分别为98.00%和63.49%,组间差异具有统计学意义(χ2=24.912,P<0.01);空洞闭合率分别为92.06%和46.03%,组间差异具有统计学意义(χ2=31.231,P<0.01)。结论:无痛纤支镜给药治疗空洞型肺结核,可使痰菌转阴和空洞闭合的时间缩短,9个月短程化疗安全可靠,效果满意。
Objective： To approah the nursing method for painless fibrobronchoscopy in the treatment for cavernous pulmonary tuberculosis and explore implementation path of short-course chemotherapy.Method： All 126 patients were randomly allocated to treatment group（M group） and control group（C group） with the random pairing method.Chemotherapy plan： M group 3HRZEAK/6HRE,administered through fibrobronchoscopy,once each week in the intensive period;chemotherapy plan of C group was the same with M group.Result： After intensive period finished,the sputum conversion rates of M group and C group were respectively 92.06%and 49.21%,comparison between both groups demonstrated statistical meaning（χ 2 =27.894,P〈0.01）;closing rates of pulmonary cavities were 67.67% and 30.16%,comparison between both groups suggested statistical meaning（χ 2 =16.811,P〈0.01）. When the session ended,the sputum conversion rates of M group and C group were respectively 98.00% and 46.03%,comparison between both groups demonstrated statistical meaning（χ 2 =24.912,P〈0.01）;closing rates of pulmonary cavities were 92.06% and 46.03%,comparison between both groups suggested statistical meaning（χ 2 =31.231,P〈0.01）.Conclusion： Painless fibrobronchoscopy in treating cavernous pulmonary tuberculosis could shorten the sputum conversion time and closing time of pulmonary cavities.Short-course chemotherapy for nine months is safe and reliable and could obtain satisfactory results,which should be widely used in clinic.
出处
《西部中医药》
2012年第10期112-114,共3页
Western Journal of Traditional Chinese Medicine
关键词
纤维支气管镜
无痛技术
肺结核
空洞
短程疗法
fibrobronchoscopy
painless technique
tuberculosis, cavernous
short course therapy
