摘要
目的探讨煤工尘肺继发肺部感染的常见易患因素和对策。方法调查90例煤工尘肺继发肺部真菌感染。结果感染发生率14.16%,主要病原菌为白色念珠菌(49.61%);年龄>60岁、严重基础疾病、抗生素滥用、激素、化疗、侵入性操作及低蛋白血症等为感染的危险因素。结论长期使用广谱抗生素和糖皮质激素是煤工尘肺患者继发肺部真菌感染的主要高危因素。
Objective To investigate the common risk factors and measures of the coal worker＇s pneumoconiosis（CWP） with sec- ondary fungal infection. Methods 127 cases of the coal worker＇s pncumoconiosis with secondary fungal infection were retrospectively an alyzed. Results The rate of nosocomial fungus infection was 14. 16%. The main germ of nosocomial fungus infection was Candida albi- cans（ the rate was 49.61% ） ; The causes of these infection were highly associated with risk factors such as age 〉 60 years old, severe pri- mary disease, application of antibiotics,hormone,immune inhibitor,chemotherapy,invasive operation, hypoproteinemia, and so on. Conclusion The main risk factor for CWP developing secondary fungal infection is long-term use of broad spectrum antibiotics and glucocorticoids. So it is time to avoid the risk factors and to take various effective control means actively.
出处
《临床肺科杂志》
2012年第11期1975-1977,共3页
Journal of Clinical Pulmonary Medicine
关键词
煤工尘肺
真菌感染
念珠菌
coal worker＇s pneumoconiosis
fungal infection
candida
