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可乐定用于老年高血压患者术后硬膜外镇痛临床观察

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摘要 目的:观察可乐定组与非可乐定组对老年高血压患者术后硬膜外镇痛的效果和不良反应。方法:60例择期下肢骨科手术患者,随机分为两组,A组吗啡5mg和左旋布比卡因112.5mg;B组可乐定100μg、吗啡5mg和左旋布比卡因112.5mg。均用0.9%氯化钠溶液稀释至100ml。观察安装止痛泵后2、4、8、12、24及40h运用视觉模拟评分法(VAS)、Ramsay镇静评分法进行疗效判定,统计镇痛期间发生高血压、低血压、心动过缓人数,记录术后发生恶心呕吐,皮肤瘙痒,呼吸抑制人数。并统计40h药物用量。结果:B组较A组在术后8-40hVAS评分低(P〈0.05),术后高血压发生率降低(P〈0.05),其他并发症比较差异无统计学意义(P〉0.05)。结论:可乐定可增强吗啡和左旋布比卡因的硬膜外术后镇痛效果,有利于老年高血压患者围木期循环稳定。
作者 胡冬云 陶洁
出处 《中外医学研究》 2012年第30期12-13,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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