摘要
目的了解补阳还五汤加减结合手法治疗慢性脑供血不足(CCCI)的临床疗效。方法按就诊时间先后顺序随机分为治疗组与对照组各50例,治疗组采用补阳还五汤加减结合手法治疗;对照组采用盐酸氟桂利嗪胶囊口服治疗,5 mg/次,2次/d。治疗90 d后进行疗效和血液流变学指标变化的比较。结果治疗组中痊愈12例,显效20例,有效15例;对照组中痊愈5例,显效11例,有效23例,差异有统计学意义(P<0.05)。治疗组与对照组血液流变学指标除血浆黏度以外,其余指标〔高切:(4.79±0.51)mPa.s vs.(5.22±0.62)mPa.s,低切:(9.59±1.81)mPa.s vs.(10.98±2.03)mPa.s,血细胞比容:(44.15±0.61)%vs.(46.58±1.48)%,纤维蛋白原:(3.02±0.53)g/L vs.(3.71±0.67)g/L〕差异均有统计学意义(P<0.05)。结论补阳还五汤加减结合手法治疗CCCI可有效改善其血液流变性,无不良反应,疗效确切显著。
Objective To observe the clinical curative effect of modified Buyang Huanwu Decoction plus manipulation in treatment of chronic cerebral circulation insufficiency （CCCI） . Methods The CCCI patients were randomly divided as trial group and control group according to the time order of visits. The 50 patients in the trial group were treated with modified Buyang Huanwu Decoction plus manipulation, and those in the control group with Flunarizine tablets orally. Results In the trial group there were 12 patients who got cured, 20 got remarkable effect, and 15 got effect, as compared with in the control group 5, 11, and 23 respectively, and the difference was significant （P 〈 0.05）. In the hemorheological indices, except for plasma viscosity, the differences of the rest ones between the trial and control groups in whole blood viscosity with high shear rates [ （4. 79 ± 0. 51 ） mPa. s vs. （5.22 ± 0. 62） mPa. s], whole blood viscosity with low shear rates [ （9.59± 1.81 ） mPa. s vs. （ 10. 98 ± 2. 03 ） mPa.s）, hematocrit [ （44. 15 ±0. 61） % vs. （46. 58± 1.48） % ], and blood fibrinogen [ （3.02 ±0. 53） g/L vs. （3.71 ± 0. 67） g/L] showed significant differences （P 〈0. 05 ）. Conclusion The modified Buyang Huanwu Decoction plus manipulation can effectively improve hemorheological indicators, with no side effects, and have definite effect in treatment of CCCI.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第28期3308-3309,3312,共3页
Chinese General Practice
关键词
慢性脑供血不足
补阳还五汤
手法
中医药治疗
Chronic cerebral circulation insufficiency
Buyang Huanwu decoction
Manipulation
TCM treatment
