摘要
目的探讨高场磁共振1 H-MRS在乳腺肿瘤定性诊断中的临床应用价值及影响因素。方法收集我院经手术病理或穿刺活检病理证实的乳腺肿瘤患者160例,共计172个肿瘤作为研究组,其中乳腺癌93个,良性肿瘤79个。全部病例均于术前行磁共振动态增强后1 H-MRS检查,回顾性分析本组病例的1 H-MRS表现及MRI诊断,并将MRI诊断结果与病理结果进行对比分析。结果 93个乳腺癌病灶中78个出现胆碱(Choline,Cho)峰。79个良性肿瘤中6个出现Cho峰。以3.23ppm处出现Cho峰(SNR≥2)为乳腺癌的诊断标准,其诊断的敏感性为83.9%,特异性为92.4%,准确率为87.8%,阳性预测值为92.9%,阴性预测值为83.0%。结论高场磁共振1 H-MRS对乳腺癌的诊断敏感性和特异性较高,在乳腺肿瘤的定性诊断中有重要应用价值。
Objective To evaluate the clinical applications of 1 H-MRS with high-field magnetic resonance imaging system in the diagnosis of breast tumor. Methods Retrospective analysis was performed on 172 Breast tumors （93 malignant, 79 benign） which had a specific pathological results. The 1 H-MRS features of them was sludied. The results of 1 H-MRS and the pathology of them were compared respectively. Results 78 items appeared Cho peak at 3.23 ppm （SNR≥2） in 93 malignant lesions. 6 items appearsed Cbo peak at 3.22 ppm （SNR≥2） in 79 benign lesions. The sensitivity, specificity, accuracy, positive predictive value, negative predictive value of Cho peak on differentiate benign from malignant lesions were 83.9 %, 92.4 %, 87.8 % ,92.9% and 83.0%, respectively. Conclusion 1 H-MRS has high diagnostic sensitivity and specificity for breast tumours. The 1 H-MRS is useful in qualitative diagnosis of breast tumours.
出处
《医学影像学杂志》
2012年第10期1681-1684,共4页
Journal of Medical Imaging
关键词
高场磁共振成像仪
氢质子波谱
乳腺肿瘤
定性诊断
High-field magnetic resonance imaging system
1 H-MRS
Breast tumor
Qualitative diagnosis
