摘要
具核梭杆菌是牙周炎主要致病菌之一,在口腔乃至全身感染性疾病中检出率极高,与临床厌氧菌感染的关系十分密切。具核梭杆菌具有明显的毒力或致病性,可通过多种机制干扰宿主防御能力,引发牙周组织破坏。本文描述了具核梭杆菌的一些重要特性,包括其生物学特征、分类和毒性特征以及主要的生物学检测手段,着重描述了聚合酶链反应技术在具核梭形杆菌检测中的应用。
Fusobacterium nucleatum, one of the main pathogens causing periodontitis, is detected extremely high in oral and even systemic infectious diseases, and closely related to the clinical anaerobic infections. It indicates significant virulence or pathogenicity through multiple mechanisms to interfere with host defense capabilities and further lead to periodontal destructions. This article describes some important characteristics of Fusobacterium nucleatum, including its biological characteristics, classification, toxicity characteristics, as well as the major biological detection methods, and focuses on the application of polymerase chain reaction technology in the detection of Fusobacterium nucleatum.
出处
《国际口腔医学杂志》
CAS
2012年第6期770-774,共5页
International Journal of Stomatology
基金
济南市科技攻关计划基金资助项目(200905034)
关键词
具核梭杆菌
细菌检测
聚合酶链反应
Fusobacterium nucleatum
bacterial detection
polymerase chain reaction
