摘要
目的:了解我院实施专项整治措施前、后抗菌药物的应用情况。方法:采用回顾性统计方法并结合ABC分析法,对我院开展抗菌药物专项整治活动前(2011年6月,整治前组)、后(2011年12月,整治后组)门诊患者的抗菌药物处方比例、住院患者抗菌药物应用率及使用强度(AUD)、Ⅰ类切口手术患者预防用抗菌药物比例等进行分析。结果:我院门诊患者抗菌药物处方比例、住院患者抗菌药物应用率分别由整治前的19.95%和57.22%下降至整治后的17.06%和51.28%;AUD均值从整治前的51.84DDDs/100人/天下降至整治后的40.67DDDs/100人/天。对AUD下降贡献度最大的是神经外科、妇科、急诊医学外科等8个A类科室,用药频度(DDDs)减少程度累计百分比达66.43%。Ⅰ类切口手术患者预防用抗菌药物比例从整治前的84.00%下降至整治后的45.01%,但与卫生部要求的30%仍有一定差距。结论:通过开展整治活动,对我院抗菌药物的合理应用有一定的促进作用,但要完全达到卫生部的要求还需进一步努力。
OBJECTIVE： To investigate the application of antibacterial in our hospital before and after special rectification. METHODS： Retrospective survey and ABC analysis method were adopted to analyze the ratio of antibacterial in outpatient prescrip- tions, the ratio and AUD of antibacterial in inpatient prescriptions and the prophylactic application ratio of antibacterial in type I incision operation before （in Jun. 2011, pre-rectification group） and after special rectification （in Dec. 2011, post-rectification group）. RESULTS： The ratio of antibacterial prescription in outpatients and the application ratio of antibacterial in inpatients de- creased from 19.95% and 57.22% before rectification to 17.06% and 51.28% after rectification. The average value of AUD dropped from 51.84 DDDs/100 persons/day before rectification to 40.67 DDDs/100 persons/day after rectification. The greatest con- tribution of departments to the decrease of AUD were 8 class A departments, such as neurosurgery department, gynecology depart- ment, emergency medicine and surgery department,etc. The accumulative percentage of DDDs reduction reached 66.43%. The pro- phylactic application ratio of antibacterial in type Ⅰ incision operation declined from 84.00% before rectification to 45.01% after rectification, which was far away from 30% of the requirement of Ministry of Health. CONCLUSION： The special rectification promotes rational use of antibacterial in our hospital. However, further development of the rectification should be made to come up to the requirement of Ministry of Health.
出处
《中国药房》
CAS
CSCD
2012年第42期3951-3953,共3页
China Pharmacy
