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肺移植受者血清可溶性白细胞介素-2受体检测的临床应用 被引量：1

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摘要 目的:探讨肺移植受者血清可溶性白细胞介素-2受体(sIL-2R)检测的临床意义以及在术后急性排斥反应和感染鉴别诊断中的应用价值。方法:采用BSA-ELISA法,动态检测18例肺移植受者术前、术后24h、术后1周、术后每月、急性排斥和感染时血清sIL-2R的浓度,将术后所测的各组结果分别与术前比较。结果:sIL-2R在肺移植术24h后血清水平均急剧升高,达(226.0±42.5)ng/L,1周后下降至(89.9±25.0)ng/L,与术前比仍偏高(P<0.01),sIL-2R在出现急性排斥反应时有高水平表达,与术前及感染时比较显著升高(P<0.01)。结论:肺移植受者血清sIL-2R的表达可以反映肺移植术后的免疫状态,有助于急性排斥反应和感染的鉴别诊断。
作者 张晓峰 陈国千 吴国荣 肖华龙 胡志刚 叶书高 朱艳红 陈静瑜
机构地区 南京医科大学附属无锡人民医院医学检验科 南京医科大学附属无锡人民医院肺移植中心
出处 《实用医学杂志》 CAS 北大核心 2012年第20期3463-3464,共2页 The Journal of Practical Medicine
基金 2008国家十一五科技支撑计划(编号:2008BAI60B05)
关键词 肺移植 可溶性白细胞介素-2受体 急性排斥反应 诊断
分类号 R655.3 [医药卫生—外科学]
  • 相关文献

参考文献9

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二级参考文献40

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共引文献27

同被引文献18

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实用医学杂志
2012年 第20期

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