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冠心病患者超敏C反应蛋白及总胆红素检测的临床意义 被引量:11

Clinical significance of serum total bilirubin and Hs-CRP in patients with coronary heart disease
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摘要 目的探讨冠心病(CHD)患者血清总胆红素及超敏C反应蛋白(hs-CRP)测定的临床意义。方法 60例冠心病患者及健康对照60例,用钒酸盐氧化法测定总胆红素,用透射比浊法测定hs-CRP浓度并做结果分析。结果冠心病患者血清总胆红素水平与健康对照组相比降低(P<0.05),hs-CRP水平与健康对照组相比增高(P<0.01)。结论血清总胆红素与冠心病的发生率呈负相关;血清C-反应蛋白与冠心病的发生率呈正相关。 Objective To investigate the clinical significance of serum total bilirubin and high sensitivity C-re- active protein(hs-CRP) in the patients with coronary heart disease(CHD). Methods The serum levels of total biliru- bin and hs-CRP were respectively determined by the vanadium-acid oxidation method and the transmission turbidime- try in 60 cases of CHD(CHD group) and 60 healthy individuals(control group). Results The serum level of total bil- iruhin in the CHD group was decreased as compared with the healthy group(P^0.05) ,while the serum level of Hs- CRP was increased as compared with the healthy group(P〈0. 001). Conclusion There is negative correlation be- tween serum total bilirubin level and the occurrence of CHD. There is positive correlation between hs-CRP and the occurrence of CHD.
出处 《检验医学与临床》 CAS 2012年第20期2544-2545,共2页 Laboratory Medicine and Clinic
关键词 冠心病 血清总胆红素 超敏C反应蛋白 coronary heart disease total bilirubin high sensitivity C-reactive protein
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  • 1黄国庆,杨宇,罗荧荃.冠脉病变严重程度与血清hs-CRP水平的相关性研究[J].疑难病杂志,2004,3(6):326-328. 被引量:18
  • 2魏美芳,吴翔,李静,吴晓晖,王益,于小红.血清TpP、hs-CRP、CKMB、cTnI在急性心肌梗死中的诊断意义[J].中国心血管病研究,2005,3(2):86-87. 被引量:10
  • 3胡敏,廖可宏,陈新瑞,秦立新.CK,CK-MB与Hs-CRP联合应用在心血管疾病诊断中的价值[J].实用预防医学,2005,12(3):498-500. 被引量:12
  • 4Swerther HA,Jackson WG,Tolan G.Associantion of low serum concentration of bilirubin with increased risk of coronary artery disease[J].Clin Chem,1997,43(1):18-23.
  • 5杜建梅.冠心病血清CRP测定及意义.医学检验与临床,2009,20(1):96-96.
  • 6Rider PM.High-sensitivity C-reactive protein:potential adjunct for global assessment in the primary prevention of cardiovascular diserse[J].Circulation,2001,103(2):1813-1818.
  • 7Devaraj S,Xu DY,Jialal 1.C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells:implications for the metabolic syndrome and atherothrombosis[J].Circulation,2003,107(1):398-404.
  • 8Hoffemeister HM,Ehler R,Buttcher E,et al.Coompari-sotn of C-reaetive Protein and termini complement complex in patients with unstable angina pectoris versus stable angina pectoris[J].Am J Cardiol,2002,89:909-912.
  • 9Koerig W.Inflammation and coronary heart disease:an o-verview[J].Cardiol Rev,2001,9:13-35.
  • 10Pearson TA, Mensah GA, Alexander RW, et al . Markers of inflammation and cardiovascular disease: application to clinical and public health practice., a statement for heahhcare professionals from the Centers for Disease Control and Prevention and the American Heart Association[J]. Circulation, 2003,107: 499-511.

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