摘要
目的探讨肥胖性不育症患者微量元素含量与精液质量的关系。方法对97例肥胖性不育症患者以及110例健康生育者采用CASAS-QH-Ⅲ计算机辅助精液分析仪进行精液质量分析;用原子吸收光谱法对全血进行Zn、Fe、Cu、Ca、Mg含量测定,并对有关数据进行统计分析。结果肥胖性不育症患者与健康生育组比较,精子密度、精子活力差异均有统计学意义(P<0.05);不育症患者全血中Zn含量低于健康生育组(P<0.01),而Cu则相反。Zn含量与精子密度、活动度呈正相关,而Cu则呈负相关;无、少精子患者Fe和Cu含量显著高于健康生育组(P<0.01)。结论肥胖性不育症患者精液密度和精子活动度均显著降低,微量元素Zn、Fe、Cu的含量与肥胖性男性不育相关。
Objective To explore the correlation between trace elements in plasma and semen quality in patients with obesity-related infertility.Methods The CASAS-QH-Ⅲ sperm analyzer was used to analyze semen quality from 97 infertile men and 110 normal men.Levels of Zn,Fe,Cu,Ca,and Mg in plasma samples were determined using atom-trapping AAS and then relevant data were statistically analyzed.Restults Sperm density and motility differed significantly（P0.05） for men with obesity-related infertility and healthy men.Levels of Zn and Cu were correlated.Levels of trace Zn in infertile men were lower than those in healthy men（P0.01） although levels of Cu were higher.Zn levels and sperm density appeared to be correlated while Cu levels and sperm density and activity were inversely correlated.Fe and Cu levels were inversely correlated with sperm density（P0.01）.Conclusion Obese patients who were infertile had significantly lower semen density and sperm activity.Levels of trace elements such as Zn,Fe,Cu,Ca,and Mg in plasma have some effect on male infertility.
出处
《中国病原生物学杂志》
CSCD
北大核心
2012年第10期754-755,761,共3页
Journal of Pathogen Biology
基金
山东省自然科学基金项目(No.ZR2011HL005)
关键词
肥胖
微量元素
男性不育
Obesity
trace element
male sterility
