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普拉洛芬滴眼液治疗干眼症疗效观察 被引量:22

Efficacy of pranoprofen eye drops in dry eyes patients
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摘要 目的:观察1g/L普拉洛芬滴眼液治疗干眼症的疗效。方法:选择我院2011-01/12门诊诊断为干眼症的患者100例,随机分成A、B两组,A组:1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用,4次/d点眼,1滴/次。B组:1g/L玻璃酸钠滴眼液单独应用,4次/d点眼,1滴/次。试验疗程为14d。所有的患者符合入选标准,用药前及用药后14d观察患者的问卷评分、SchirmerI试验、角膜荧光素染色评分。比较两组的结果,进行统计分析。结果:1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用治疗干眼症患者的效果明显优于单纯使用1g/L玻璃酸钠滴眼液治疗组,两组结果差异有统计学意义。结论:1g/L普拉洛芬滴眼液治疗干眼症,对于缓解症状,改善角膜情况效果良好。 AIM:To observe the effect of 1g/L pranoprofen eye drops in the treatment of dry eye.METHODS:A total of 100 dry eyes patients,from the outpatient department in our hospital between January and December of 2011,were randomly divided into two groups:group A was treated by 1g/L pranoprofen drops combined with 1g/L sodium hyaluronate eye drops,1 drop each time,4 times/d for each eye;group B was treated by 1g/L sodium hyaluronate eye drops alone,1 drop each time,4 times/d,for each eye,All patients met the inclusion criteria before treatment and were observed before and after 14 days of treatment with questionnaire scores,Schirmer Ⅰ trial,corneal fluorescein staining scores.The results of the two groups were compared for statistical analysis.RESULTS::The effect of 1g/L pranoprofen eye drops combined 1g/L of sodium hyaluronate eye drops was significantly better than that of 1g/L of sodium hyaluronate eye drops in the treatment of dry eye patients.There was significant difference between two groups.CONCLUSION:1g/L pranoprofen is effective for dry eye to relieve symptoms and improve corneal situation.
作者 王伟鹏
出处 《国际眼科杂志》 CAS 2012年第11期2231-2232,共2页 International Eye Science
关键词 干眼症 普拉洛芬 玻璃酸钠 炎症 dry eye pranoprofen sodium hyaluronate inflammation
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参考文献2

  • 1Letup M, Baudonin C, Baum J, et al . The definition and classification of dry eye disease : report of the definition and classification subcommittee of the international dry eye workshop. Ocul Suoe 2007 ;5 (2) :75-92.
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