摘要
目的了解我院2010～2011年重症监护病房(ICU)鲍曼不动杆菌感染/定植情况及其耐药趋势,为临床合理使用抗菌药物和医院感染的预防、控制提供重要依据。方法采用回顾性和前瞻性监测方法,查阅临床资料和临床微生物检测报告,统计分析ICU鲍曼不动杆菌感染/定植情况及耐药性。结果 273株鲍曼不动杆菌中47株为定植菌,定植率为17.22%;226株为感染菌株,感染率为82.77%(引起医院感染占71.42%,院外感染占11.35%);体外药敏试验结果显示273株鲍曼不动杆菌对氨苄西林、头孢替坦、呋喃妥因耐药率100%,碳青霉烯类、头孢类、氨基糖苷类抗菌药物耐药率分别为95.24%、96.61%和75.82%。结论鲍曼不动杆菌是引起医院感染的重要条件致病菌,具有耐药性强、耐药谱广的特点,临床上应加强对多重耐药鲍曼不动杆菌实时监测和预防控制。
Objective To analyze infection, colonization and drug-resistance status of 273 Acinetobacter baumannii in inten- sive care unit from 2010 to 2011 ,and to provide information for reasonable use of antibacterial agents and control of nosocomial infec- tions. Methods After consulting clinical data and examination reports of clinical microbiology, the infection, colonization and drug-re- sistance status of Acinetobacter baumannii in intensive care unit was statistically analyzed by using retrospective and prospective meth- ods. Results Forty-seven of 273 Acinetobacter baumannii were colonization bacteria, with colonization rate of 17.22%. The other 226 strains were infectious bacteria and infectious rate was 82. 77% ,including 195 strains of nosocomial infections （71.42%）and 15strains of out-hospital infections （11.35% ）. The resistance rate of ampicillin, cefotetan, nitrofurantoin against Acinetobacter banmannii was 100%. The resistance rate of carbapenems, cephalosporins and aminoglycoside was 95.24%, 95.60% and 75.82% respectively. Con- clusions Acinetobacter baumannii is a main opportunistic pathogen causing nosocomial infections with strong drug resistance and wide drug resistance spectrum. We should pay more attention for monitoring and preventing multidrug resistance Acinetobacter baumannii.
出处
《实用医院临床杂志》
2012年第6期102-104,共3页
Practical Journal of Clinical Medicine
关键词
鲍曼不动杆菌
感染
定植
抗菌药物
耐药
重症监护病房
Acinetobacter baumannii
Infection
Colonization
Antibacterial agents
Drug resistance
Intensive care unit
