摘要
目的探讨结肠癌患者淋巴结数目和TNM病理分期对其预后的影响。方法回顾性研究537例结肠癌患者的临床病理资料,对影响结肠癌患者预后的肿瘤直径、淋巴结转移数、病理类型、TNM分期等因素进行单因素和多因素logistic回归分析。结果结肠癌患者不同病理类型间淋巴结转移度差异有统计学意义(P<0.01),其中印戒细胞癌的转移度最高达到73.91%;肿瘤直径>8cm的5年存活率仅为47.24%;是否有淋巴结转移对患者预后的差异有统计学意义(P<0.01),存在淋巴结转移的患者3年和5年存活率分别为48.24%和35.13%。结论淋巴结转移是影响结肠癌患者预后生存期的关键因素。
Objective To explore the effect of lymph nodes and TNM pathology stage on prognosis of patients with colon caner. Methods Retrospective study of clinical pathological information of 537 colon cancer patients, and conduct uni-variate and multivariate logistic regression analysis of tumor diameter, number of lymph node metastasis, pathological type,TNM stage and other factors affecting the prognosis of colon cancer patients. Results Degree of lymph node metas- tasis has significantly statistical difference between different pathological types of colon cancer patients （ P 〈 0. 01 ）, sig-net ring cell carcinoma＇metastasizing degree was up to 73.91% ;Five -year survival rate of tumor size 〉 8cm was only 47.24% ;The prognosis of patients with lymph node metastasis or not has significantly statistical difference（ P 〈 0. 01 ）, three and five-year survival rate of patient with lymph node metastasis was 48.24% and 35.13% , respectively. Con-clusions Lymph node metastasis is the key factor that affecting the prognosis of colon cancer patients.
出处
《医药论坛杂志》
2012年第11期15-17,共3页
Journal of Medical Forum
关键词
结肠癌
淋巴结数
TNM分期
Colon cancer
Lymph nodes
TNM pathology stage
