3Bruno Bergamasco, Claudio Villardita, Renato Coppi. Effects of ide- benone in elderly cognitive decline. Results of a clinical trial subjects with multicentre[J]. Arch Gerontol Geriatr. 1992, 15:279 -286.
4Bergamasco B, Scarzella L, La Commare P. Idebenone, a new drug in the treatment of cognitive impairment in patients with dementia of the Alzheimer type [ J ]. Funct Neurol, 1994, 9 (3) : 161 - 168.
5G. Weyer, R.M. Babej- D? lle, D. Hadler, et al. A controlled study of 2 doses of Idebenone in the treatment of Alzheimer's disease [ J]. Neuropsychobiology, 1997, 36 : 73 - 82.
6Nicholas A Di Prospero, Angela Baker, Neal Jeffries, et al. Neurologi- cal effects of high - dose idebenone in patients with Friedreich's ataxia : a randomised, placebo - controlled trial [ J ]. The Lancet Neurology, 2007, 6(10) : 878 -886.
7Aben I, Denollet J, Lousberg R, et al. Personality and vulnerabili-ty to depression in stroke patients: a 1-year prospective follow-upstudy[J]. Stroke, 2002, 33 (10): 2391--2395.
8恽晓平.康复疗法评定学[M]北京:华夏出版社,2007.
9Gordon WA, Hibbard MR. Post stroke depression: on examination of the litoveture[J].Arch Phys Rehabil, 1997,78:658--659.
4Abdel Baky NA,Zaidi ZF,Fatani AJ,et al. Nitric oxide pros andcons: The role of L - arginine, a nitric oxide precursor,and idebenone,a coenzyme - Q analogue in ameliorating cerebral hypoxia in rat [ J ].Brain Res Bull, 2010,83(1 -2) :49 -56.
5McDaniel DH, Neudecker BA, DiNardo JC, et al. Idebenone: a newantioxidant - Part I. Relative assessment of oxidative stress protectioncapacity compared to commonly known antioxidants[ J] . J Cosmet Der-matol, 2005,4 (1):10-17.
6Becker C, Bray - French K, Drewe J. Pharmacokinetic evaluation ofidebenone[ J]. Expert Opin Drug Metab Toxicol, 2010,6(11) : 1437 -1444.
7Gutzmann H,Ktihl KP, Hadler D, et al. Safety and efficacy of ide-benone versus tacrine in patients with Alzheimer's disease: results of arandomized,double - blind,parallel - group multicenter study [ J ].Pharmacopsychiatry, 2002,35 (1 ) :12 -18.
8Voronkova KV, Meleshkov MN. Use of Noben (idebenone) in thetreatment of dementia and memory impairments without dementia[ J].Neurosci Behav Physiol, 2009,39(5) :501 -506.
9De Ryck A, Brouns R, Fransen E, et al. A prospective study on theprevalence and risk factors of poststroke depression[ J]. Cerebrovasc DisExtra, 2013,3(1) :1 -13.
10Park JH, Kim BJ, Bae HJ, et aL Impact of post - stroke cognitive im-pairment with no dementia on health - related quality of life [ J ]. JStroke, 2013,15(l):49-56.
