摘要
目的:探讨纯中药浓缩胶囊肝毒清对慢性乙型肝炎的临床疗效。方法:48例慢性乙型肝炎患者每次口服肝毒清肢囊8粒,每日3次,30例对照组患者每次口服灭澳灵片6片,每日3次。两组均于治疗前和治疗后的0、3、6个月检查ALT、AST、A/G、TBil、HBV5项指标及HBV-DNA(PCR法)进行对比。结果:肝毒清组总有效率89.5%,对照组为66.6%;HBeAg、HBV-DNA阴转率,肝毒清组为48.5%、45.9%,对照组为23.8%和21.7%;均差异显著(P<0.05)。结论:肝毒清能有效改善慢性乙型肝炎患者临床症状和促使HBV-DNA转阴,是治疗慢性乙型肝炎较为理想的药物。
Aim : To evaluate the clinical curative effects of the capsule preparation concentrated from pure herbal medicine (named Ganduqing, GDQ) for treating chronic hepatitis B. Methods: In group of using GDQ which included 48 cases of chronic hepatitis B, every patient took 8 capsules of GDQ orally per time and three times a day. In control group including 30 cases of chronic hepatitis B,every patient took 6 tablets of Mieaoling(MAL) orally per time and three times a day. In pre-treat and 3, 6 months post-treat, the items of ALT. AST, A/G, TBili markers of hepatitis B and HBV-DNA (by PCR method) were assayed respectively in all patients and contrasted between two groups. Results: The totall rates of efficiency for treating chronic hepatitis B were 89. 5% in the group of using GDQ and 66. 6% in control group. The incidences of turning negative for HBeAg and HBV-DNA in the group of using GDQ were 48. 5% and 45. 9% respectively which were higher than 23. 8% and 21. 7% in control group significantly (P<0. 05). Conclusion: GDQ can alleviate the symptoms of patients with chronic hepatitis B effectively and improve turning negative for HBeAg and HBV-DNA in patients with chronic hepatitis B. It is a more appropriate medicine for treating chronic hepatitis B.
出处
《中西医结合肝病杂志》
CAS
2000年第3期15-16,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
