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三阴乳腺癌与非三阴乳腺癌X线及病理特征分析 被引量:11

Mammographic features and histopathological characteristics of triple negative breast cancer and non-triple negative breast cancer
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摘要 目的与非三阴乳腺癌(non-TNBC)比较,探讨三阴乳腺癌(TNBC)的X线表现及病理特征。方法回顾性分析经病理证实的574例乳腺癌患者资料,对比分析81例TNBC(TNBC组)与493例non-TNBC患者(non-TNBC组)的临床、病理特征及X线表现。结果 TNBC组织学分级以中、高级别为主,其中53.09%(43/81)发生腋窝淋巴结转移,高于non-TNBC组(39.96%,197/493,P<0.05)。与non-TNBC组相比,TNBC病变体积较大,多为单纯肿块型,少见钙化(P<0.05),肿块型TNBC瘤体多为类圆形,边缘光滑,较少见不规则形及毛刺(P<0.05)。结论 TNBC与non-TNBC在X线表现及病理特征方面存在一定差异,了解其特征有助于诊断TNBC。 Objective To explore the mammographic features and histpathological characteristics of triple negative breast cancer (TNBC) compared with non-triple negative breast cancer (non-TNBC). Methods A total of 574 patients with his topathologically confirmed breast cancer were analyzed retrospectively. The clinical, histopathological and mammographic imaging characteristics of TNBC patients (n= 81) were analyzed and compared with those of non-TNBC patients (n= 493). Results Most of TNBC showed intermediate and high histological grade. The percentage of lymph node metastasis in TN BC group (43/81, 53, 09%) was higher than that of non-TNBC group (197/493, 39.96 %, P〈0.05). Tumors in TNBC group were larger than non-TNBC group, usually presented as a mass with less calcifications (P〈0.05). The masses of TNBC frequently presented as oval and smooth margin, with less irregular and burr (P〈0.05). Conclusion There are some differences between TNBC and non-TNBC in pathology and radiology. Understanding these characters might he use- ful to diagnose TNBC.
作者 李丽娟 黎庶
出处 《中国医学影像技术》 CSCD 北大核心 2012年第11期2015-2018,共4页 Chinese Journal of Medical Imaging Technology
关键词 乳腺肿瘤 乳房X线摄影术 免疫组织化学 Breast neoplasms Mammography Immunohistochemistry
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共引文献197

同被引文献128

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