摘要
目的评价柏黛膏抗菌活性及其与青霉素的协同抑菌效能。方法最低抑菌浓度(MIC)测定用琼脂二倍稀释法。结果柏黛膏与青霉素对金黄色葡萄球菌与大肠杆菌具有很好的抗菌活性,柏黛膏+青霉素对金黄色葡萄球菌与大肠杆菌抗菌MIC50和MIC90值分别为0.25,4.00 mg.L-1;1,4 mg.L-1。结论柏黛膏与青霉素对金黄色葡萄球菌、大肠杆菌均有协同抗菌功效。
Objective inal extract for exterior benzylpenicillin sodium centration （MIC） was To evaluate the antibacterial activity of the medic- application of BaifDai （MEEAB） combination with in vitro . Methods The minimum inhibitory con- determined by use of two -fold dilution method. Results There was good antibacterial activity of MEEAB combination with benzylpenicillin sodium against Staphylococcus aureus and Escherichia coli. The MIC of MEEAB plus benzylpenieillin sodium against Staphylococ- cus aureus and Escherichia coil were 0. 25,4. 00 mg· L^-1 ;1,4 mg· L^-1 , respectively. Conclusion MEEAB plus benzylpenicillin sodium had more synergy inhibitory effect on the Staphylococcus aureus and Escherichia coli.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2012年第10期765-766,共2页
The Chinese Journal of Clinical Pharmacology
基金
军队"十一五"科研基金资助项目(No.B086)
关键词
柏黛膏
对葡萄球菌的体外抗菌活性
协同作用
毒霉素
medicinal extract for exterior application of BaifDai
anti- bacterial activity on the Staphylococcus aureus
synergy effect
benzylpenieillin
