摘要
目的探讨肺炎支原体（MP）感染与咳嗽变异性哮喘（CVA）发病的临床相关性。方法选取来我院就诊的68例CVA患者作为观察组，并选择同时期进行就诊的急性上呼吸道感染患者70仍作为对照组。检测两组患者的肺炎支原体抗体（MP－IgM）及观察组患者的嗜酸粒细胞（EOS）计数、血泊总IgE水平。结果观察组患者的MP－IgM阳性率33．82％明显高于对照组14．29％（P〈O．01）；观察组中MP－IgM阳性患者的血清总IgE水平及EOS均明显高于MP－IgM阴性患者（P〈0．01）。结论MP感染与CVA发病密切相关，MP是诱发CVA的主要病原体之一。
Objective To investigate the clinical relevance of mycoplasma pneumoniae （MP） infection and pathogenesis of cough variant asthma （CVA）. Methods 68 patients with CVA in our hospital were considered as the observation group, and 70 patients with acute upper respiratory infection at the same period were considered as the control group. The mycoplasma pneumoniae antibody （MP- IgM） in the two groups and eosinophil （EOS）, serum IgE levels of the observation group were determined. Results The positive rate of MP-IgM in the observation group was 33.82% significantly higher than 14.29% of the control group （ P 〈O. 01）, in the observation group, serum IgE levels and EOS in the MP-IgM positive patients were higher than MP-IgM-negative patients （P 〈 0.01 ）. Conclusions MP infection has closely related with CVA, and MP is one of the maior pathogens to induce CVA.
出处
《国际呼吸杂志》
2012年第21期1605-1606,共2页
International Journal of Respiration
关键词
肺炎
支原体感染
咳嗽变异性哮喘
相关性
Pneumoniae
Mycoplasma pneumoniae infection
Cough variant asthma
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