摘要
预防接种是预防控制针对传染病最经济、最有效的干预措施。随着扩大国家免疫规划的实施,疫苗覆盖范围进一步扩大,疫苗种类不断增多,接种剂次持续增加,出现疑似预防接种异常反应(Adverse Event Following Immunization,AEFI)的病例数可能有所增加,而过敏反应、神经系统反应等AEFI受到普遍关注。目前国内外尚无完善的、操作性较强的AEFI诊断标准,各地调查诊断掌握不尽相同,监测报告质量参差不齐,这给规范处理预防接种异常反应带来了不便。现主要通过查阅国内外有关AEFI监测、报告、调查、诊断等方面的文献,进行提炼分析,阐述目前国内外AEFI监测报告和诊断标准的研究现状,为探索制定预防接种异常反应的诊断标准提供参考。
Vaccination is the most economic and effective means for infectious disease control and prevention. With the implementation of the national expand program on immunization, more EPI vaccines integrated, and more doses vaccinated, the cases of adverse event following immunization may increased as well, and allergic reaction, nervous system response, and other adverse event following immunization are paid more attention. There was no perfect and operational diagnosis standard of adverse event following immunization. Different standard of investigation and diagnose in various regions result in a great challenge for ized standardized deal with AEFIs. This paper mainly through review of domestic and foreign literature relevant monitoring, reporting, surveying and the diagnosis of AEFIs, to refine analysis, outline the research status of international and domestic diagnosis standard on AEFIs to provide reference for formulating and perfect diagnosis standard on AEFIs.
出处
《中国疫苗和免疫》
CAS
2012年第5期465-468,共4页
Chinese Journal of Vaccines and Immunization
基金
国家科学技术艾滋病和病毒性肝炎等重大传染病防治重大专项疫苗临床试验评价技术平台构建的研究课题(编号:2009ZX10004-806)
关键词
预防接种
疑似预防接种异常反应
诊断标准
Prophylactic immunization
Adverse event following immunization（AEFIs）
Diagnosis standard
