摘要
自固化磷酸钙 (CPC)是数年前在美国研制成功的一种非陶瓷型羟基磷灰石类 (HAP)人工骨材料。它克服了陶瓷型 HAP烧结形成、修整困难等缺点 ,具有制备容易、使用方便等优点。1991年以来 ,CPC开始在临床试用 ,修复颅骨 ,获得满意效果。本文报告了 CPC的最新研究结果 ,包括固化过程及固化工艺的研究 ,快速凝固型、抗水型 CPC的研究 ,有机复合 CPC水门汀的研究和作为载体缓释多种药物的体外试验结果等。随着研究范围的不断深入和扩大 。
Self setting calcium phosphate cement(CPC) is a non ceramic form of hydrxyapatitic artificial bone material (HAP) which was first exclusively produced in America several years ago. CPC is free from the drawbacksto ceramic HAP,including sintering and difficulties in shaping. CPC has the characteristics of simple producing and easy applyication.In 1991,the clinical application of CPC to repairing the calvarial bone defects was approved,and the results reportedly so far were good or excellent.This paper presents the latest progress in the studies of CPC,concerning the probing into the setting process,the producing of fast setting and non decayed types of CPC,the studies of organic compound CPC,the in vitro results of CPC as a drug delivery system,etc.As the research goes on deeply and broadly,CPC is hopefully becoming a standard material in repairing bone defects at the non or low bearing site in the future.
出处
《生物医学工程学杂志》
CAS
CSCD
北大核心
2000年第1期80-83,共4页
Journal of Biomedical Engineering
