摘要
目的探讨普萘洛尔治疗婴幼儿血管瘤的效果和安全性。方法2011年4月至2012年2月，对42例婴幼儿血管瘤进行口服普萘洛尔治疗，2．0mg（kg·d），疗程3～9个月，并进行疗效评定和安全性评价。结果患儿口服普萘洛尔1周后，肿物生长得到有效控制。疗效评定：优10例（23．81％），好18例（42．86％），中13例（30．95％），差1例（2．38％），有效率为66．67％。其中深部血管瘤的疗效明显优于浅部和混合型血管瘤。9．52％（4／42）患儿有轻微不良反应，均于1周内自行消失。结论普萘洛尔口服治疗婴幼儿血管瘤的方法有效，不良反应少，安全性较好。
Objective To observe the clinical effect and safety of Propranolol for treating infantile he- mangiomas. Methods From Apr 2011 to Feb 2012, 42 patients with infantile hemangiomas were was orally administered with Propranolol at 2.0 mg/（ kg· d）. The total time of therapy was 3 months to 9 months. The efficacy and safety of medication were evaluated after finishing treatment. Results The hemangioma growth was controlled in all the patients at 1 week after treatment. Response to propranolol therapy was excellent in 10 patients （23.81%） ,good in 18 patients （42.86%）, fair in 13 patients （30.95%） and poor in 1 pat ient （2.38%）. The therapeutic effect of deepseated hemangiomas was superior to that of mixed hemangiomas and superficial lesions. Minor side effects were happened in 9.52% （ 4/42 ） of patients, which disappeared within one week without special handling. Conclusion Oral propranolol is effective and safe in the treatment of infantile hemangioma with minor side effect.
出处
《中国美容整形外科杂志》
CAS
2012年第11期670-673,共4页
Chinese Journal of Aesthetic and Plastic Surgery
关键词
普萘洛尔
婴幼儿血管瘤
临床研究
Propranolol
Infantile hemangioma
Clinical research
