摘要
目的:观察大黄利胆胶囊治疗胆囊术后综合征的临床疗效。方法:144例诊断胆囊术后综合征患者分为观察组及对照组,观察组和对照组分别口服大黄利胆胶囊和消炎利胆片治疗6个月,观察临床疗效及前后VAS评分自身对照。结果:观察组患者主要症状腹痛、恶心较对照组均有明显缓解,总有效率分别为88.9%vs.75.0%(X2=12.517,P=0.000)、97.2%vs.88.9%(X2=4.923,P=0.043)。对照组纳差症状缓解优于观察组,但无统计学差异,86.1%vs.77.0%(X2=1.077,P=0.664)。观察组与对照组患者右上腹胀闷治疗前平均VAS分值无显著差异(7.02 vs.6.14,t=0.621,P=0.933),治疗后平均VAS分别为2.12和4.15,观察组疗效显著优于对照组(t=2.079,P=0.020)。结论:大黄利胆胶囊治疗胆囊术后综合征有确切疗效。
Objective：To investigate the effects of rhubarb choleretic capsule（RCC） on Post-cholecystectomy syndrome（PCS）.Methods：144 cases were diagnosed as PCS and were divided into two groups,which were the study group and the control group.Treatment with RCC and Xiaoyan Lidan tablets respectively 6 months to determine the efficacy on clinic symptoms and Visual analogue scales（VAS） via case control study.Results：The main symptomatic outcome of study group are improving more significantly than control group,which efficiency rate of abdominal pain,nausea,are 88.9% vs.75.0%（X2=12.517,P=0.000）,97.2% vs.88.9%（X2=4.923,P=0.043）,respectively.The anorexia outcome of control group are improving more than study group which are 86.1% vs.77.0%,but no significant difference（X2=1.077,P=0.664）.The level of VAS according to right upper abdominal pain of study group are improving more greatly than control study（before-average VAS 7.02 vs.6.14 t=0.621,P=0.933;after-average VAS 2.12 vs.4.15,（t=2.079,P=0.020）.Conclusion：Treating PCS with rhubarb choleretic capsule（RCC） has a good effect.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2012年第21期2531-2534,共4页
Chinese Journal of New Drugs
基金
国家自然科学基金(81150031)
