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2008-2011年剖宫产围手术期抗菌药物使用分析 被引量:4

Analysis of perioperative use of antimicrobial drugs in cesarean section from 2008 to 2011
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摘要 目的:了解我院近4年剖宫产围手术期抗菌药物使用情况,评价用药的合理性。方法:随机抽查2008-2011年我院剖宫产病历195份,从抗菌药物品种的选择、首次用药时机、使用疗程、抗菌药物费用等方面进行分析。结果:195例剖宫产手术患者中,100%预防性使用抗菌药物。2008年凭经验预防用药,首剂均在术后开始,选用青霉素钠或林可霉素联用甲硝唑,平均用药3.21 d。2009年开始规范用药,单用头孢唑啉钠或克林霉素,首剂于断脐后使用,平均用药2.36 d。4年抗菌药物费用占住院费用比均<1.00%。结论:4年来,我院剖宫产围手术期抗菌药物使用逐年规范,但预防用药时间偏长,欠合理。 Objective: To investigate the use of antibacterial drugs during caesarean operation in the recent four years in our hospital,and to evaluate the rationality of drug use.Methods: One hundred and ninety-five cesarean section cases from 2008 to 2011 in our hospital were randomly sampled.The choice of antibiotics,medication time,medication duration,antimicrobial drug cost and other aspects were analyzed.Results: All of the 195 cases prophylacticly used antibacterial drugs.In 2008,the drugs were chosen based on experience,the first dose was given after the cesarean section,penicillin sodium or lincomycin was used in combination with metronidazole,and the average duration was 3.21 days.Since 2009,the use of antimicrobial drugs was standardized.Cefazolin sodium or clindamycin DX was used,the first dose was given after umbilical cord cutting,and the average duration was 2.36 days.The ratios of antimicrobial drug costs to hospitalization expense in the four years were all less than 1.00%.Conclusion: The perioperative antimicrobial use for caesarean operation in the last four years in our hospital has been changing for more rational,but the medication duration was too long.
出处 《中国新药杂志》 CAS CSCD 北大核心 2012年第21期2573-2575,共3页 Chinese Journal of New Drugs
关键词 剖宫产 围手术期 抗菌药物 预防用药 使用分析 cesarean section perioperative period antimicrobial drugs preventive drug use drug utilization analysis
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