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LEEP刀联合重组人干扰素α-2b凝胶治疗慢性宫颈炎疗效研究 被引量:28

Study of efficacy of LEEP knife combined with recombinant human interferon α-2b gel in the treatment of chronic cervicitis
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摘要 目的探讨LEEP刀联合重组人干扰素α-2b凝胶治疗慢性宫颈炎的临床疗效,旨在为临床治疗提供指导理论支持。方法选取我院2011年1月~2012年1月收治的慢性宫颈炎患者200例作为观察对象,随机分为观察组(LEEP刀联合重组人干扰素α-2b凝胶治疗)和对照组(重组人干扰素α-2b凝胶治疗),每组各100例,比较两组患者的临床疗效及治疗后的出血率、感染率及阴道排液时间。结果观察组的总有效率明显高于对照组,差异有统计学意义(P〈0.05)。观察组治疗后的出血率、感染率明显低于对照组(P〈0.05),阴道排液时间明显短于对照组(P〈0.05)。观察组治疗后3、6个月的创面愈合率均明显高于对照组(P〈0.05)。结论 LEEP刀联合重组人干扰素α-2b凝胶治疗慢性宫颈炎疗效确切,不良反应少,值得临床推广应用。 Objective To investigate the clinical efficacy of LEEP knife combined with recombinant human interferon alfa-2b gel in the treatment of chronic cerviciti,in order to provide theoretical support for clinical treatment.Methods 200 cases of patients with chronic cervicitis in our hospital from January 2011 to January 2012 were selected and randomly divided into the observation group(LEEP knife combined with recombinant human interferon α-2b gel treatment) and the control group(recombinant human interferon α-2b gel treatment),each group had 100 cases.Clinical efficacy and the rate of bleeding,infection and vaginal discharge time after treatment were compared between the two groups.Results The total effective rate in the observation group was significantly higher than that in the control group,the difference was statistically significant(P 0.05).After treatment the bleeding rate,infection rate in the observation group were significantly lower than those in the control group(P 0.05),and the vaginal discharge time was significantly shorter than that in the control group(P 0.05).The wound healing rates at 3 and 6 months after treatment in the observation group were significantly higher than those in the control group(P 0.05).Conclusion The efficacy of LEEP knife combined with recombinant human interferon α-2b gel in the treatment of chronic cervicitis is definite,which has fewer adverse reactions.It is worthy of clinical application.
出处 《中国医药导报》 CAS 2012年第31期48-49,54,共3页 China Medical Herald
关键词 慢性宫颈炎 LEEP刀 重组人干扰素Α-2B凝胶 Chronic cervicitis LEEP knife Recombinant human interferon α-2b gel
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