摘要
目的探讨未足月胎膜早破(PPROM)破膜孕周及不同潜伏期长短对妊娠结局的影响及临床意义。方法回顾性分析434例孕28～37周PPROM孕产妇和新生儿的临床资料,根据孕产妇发生PPROM的孕周将所有病例分为28～33周(A组)和34～37周(B组)两组,并根据潜伏期分别将两组患者分为﹤48h和﹥48h。总结其临床特征及围产结局。结果 B组母婴结局优于A组,差异有统计学意义(P<0.05)。A组潜伏期大于48h孕妇分娩后发生产褥感染和绒毛膜羊膜炎概率高于潜伏期小于48h孕妇(P<0.05),潜伏期大于48h胎儿窒息、肺部感染以及呼吸窘迫综合征的发生率优于潜伏期小于48h者(P<0.05)。B组潜伏期大于48h孕妇分娩后发生产褥感染和绒毛膜羊膜炎概率高于潜伏期小于48h孕妇(P<0.05),新生儿各项指标组内对比差异无统计学意义(P>0.05)。结论针对未足月胎膜早破发生的相关因素采取相应的临床处理,增加孕期保健,综合治疗,可减少母婴病率,改善孕妇及早产儿预后。
Objective To study the effect and clinical significances of different gestational weeks and latent period on pregnancy outcomes in preterm premature rupture of membrane （PPROM）. Methods According to gestational weeks, 434 patients with PPROM of 28～37 weeks were divided into group A （28～33 weeks） and group B （34～37 weeks）, which were further divided into 48 h subgroup and 48 h subgroup according to latent period. The clinical features and perinatal outcome were analyzed. Results The pregnancy outcome was significantly better in group B than group A （P0.05）. In group A, the incidences of puerperal infection and chorioamnionitis were significantly higher in 48 h subgroup than 48 h subgroup （P0.05）, while the incidences of fetal distress, pulmonary infection and respiratory distress syndrome were significantly lower in 48 h subgroup （P0.05） than 48 h subgroup. In group B, the incidences of puerperal infection and chorioamnionitis were significantly higher in 48 h subgroup than 48 h subgroup （P0.05）, while no statistically significant difference was found in the indexes of neonates （P0.05）. Conclusion Adopting the relative clinical treatment and strengthening the gestataional health, based on the relative factors leading to preterm premature rupture of membranes, may reduce the morbidity of maternal and neonates and improve the prognosis of preterm neonates.
出处
《海南医学》
CAS
2012年第22期46-48,共3页
Hainan Medical Journal
关键词
未足月胎膜早破
孕周
潜伏期
妊娠结局
Preterm premature rupture of membrane
Gestational weeks
Latent period
Pregnancy outcomes
