摘要
目的探讨胎膜早破对母婴结局的影响。方法详细记录笔者医院2003年1月～2010年12月收治的2405例单胎胎膜早破孕妇的临床资料,观察母婴感染率。按破膜距分娩时间长短将胎膜早破孕妇分为<12h组和≥12h组,观察破膜距分娩时间与绒毛膜羊膜炎发生率、母婴感染率的关系。比较83例感染孕妇和2322例未感染孕妇的新生儿感染发生率。将83例伴有新生儿感染的胎膜早破孕妇分成未足月胎膜早破组和足月胎膜早破组,观察两组新生儿的临床结局。结果 2405例胎膜早破患者中,孕妇感染83例,占3.45%,新生儿感染72例,占2.99%。与破膜距分娩时间<12h组相比,≥12h组绒毛膜羊膜炎发生率显著增加(P<0.01),母婴感染率明显增高(P<0.01)。感染孕妇组的新生儿感染率高于未感染孕妇组。与足月组相比,未足月胎膜早破组胎儿宫内窘迫率及新生儿感染率明显升高(P<0.05),但两组分娩方式无显著差异(P>0.05)。结论胎膜早破严重影响母婴健康,发生感染的孕妇更易发生新生儿感染。对于不同孕周、破膜时间长短不同的胎膜早破孕妇应采取相对应的治疗措施以降低母婴感染并发症。
Objective To observe the influence of premature rupture of membranes （PROM） on neonatal and maternal outcomes. Methods From January 2003 to December 2010, the clinical data of 2405 cases of singleton pregnancy with PROM were recorded, and the incidence rate of neonatal and maternal infection were analyzed. All cases were stratified according to the duration of PROM into two groups： 〈 12h ands〉 12h,and the incidence of chorioamnionitis, neonatal and maternal infection were compared. All cases were divided into two groups with 83 cases of PROM with maternal infection in the observation group and 2322 cases without maternal infection in the control group. We compared the incidence rate of neonatal infection. Thirty - one preterm newborns and 52 term newborns with maternal infection were analyzed for the delivery option and neonatal outcome. Results Among 2405 cases, 83 maternal infections and 72 neonatal infections were found, respectively. The incidence rate of chorioamnionitis,neonatal and maternal infection when the membranes ruptured over 12 hours was higher than when it was less than 12hours （ P 〈 0.01 ）. The incidence rate of neonatal infection was higher in the obser- vation group. Among 83 cases of PROM with neonatal infections, fetal distress and neonatal infection occurred at a significantly higher in- cidence in preterm PROM group（ P 〈 0.05）, but there was no significant difference in delivery option（P 〉 0.05 ）. Conclusion PROM is harmful to the health of neonatal and maternal. Maternal infection highly suggests the possibility of neonatal infection. The patients of PROM with different gestation weeks and time from membrane rupture to delivery should be treated with different methods to reduce the in- cidence of neonatal and maternal infection.
出处
《医学研究杂志》
2012年第11期172-175,共4页
Journal of Medical Research
关键词
胎膜早破
感染
绒毛膜羊膜炎
妊娠结局
Premature rupture of membranes
Infection
Chorioamnionitis
Pregnancy outcome
