摘要
目的探讨左心室扩大患者可能的临床危险因素。方法冠状动脉造影(CAG)患者96例,46例诊断左心室扩大(A组),50例左心室正常(B组)。观测项目:血糖(BG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C),低密度脂蛋白胆固醇(LDL-C),甘油三酯(TG),尿酸(UA),白细胞(WBC),高敏C反应蛋白(hs-CRP),ST段压低程度(STD),冠脉前降支血流时间(LADET),左心室舒张末内径(LVDD),左心射血分数(LVEF)值。结果 A组2型糖尿病(T2DM)患者比例高于B组(69.6%vs.28.0%)(P<0.01)。A组高血压患者比例高于B组(76.1%vs.54.0%)(P<0.05)。A组年龄、WBC、UA、BG、hs-CRP、STD、LADET、EF、LVDD均显著高于B组(P<0.01)。Linear回归分析显示,T2DM、年龄、LADET是左心室扩大的独立危险因素(P<0.05或P<0.01)。结论T2DM、年龄、LADET是左心室扩大的独立危险因素。
Objective To investigate the risk factors possibly for left ventricular enlargement without definite causes in 46 cases.Methods A total of 96 patients underwent coronary arteriongraphy,who was divided into two groups of A（46 cases diagnosed as left ventricular enlargement） and B（50 cases with normal left ventricul）.The measurements included blood glucose（BG）,uric acid（UA）,total cholesterol（TC）,triglyceride（TG）,low density lipoprotein cholesterol（LDL-C）,high density lipoprotein cholesterol（HDL-C）,white blood cell（WBC） and high-sensitivity C-reactive protein（hs-CRP）.The depression of ST segment electric tension（STD）,left anterior descending branch engorge time（LADET）,left ventricular end-diastolic diameter（LVDD） and left ventricular ejective function（LVEF） were detected as well.Results The percentage of 2-type diabetes mellitus（T2DM） was higher in group A than that in group B（69.6% vs.28.0%）（P0.01）.So did that of hypertension（76.1% vs.54.0%）（P0.05）.The age,WBC,UA,BG,hs-CRP,STD,LADET,EF,LVDD were all obviously higher in group A than those in group B（P0.01）.The linear regression analysis showed that T2DM,age and LADET were the independent risk factors for left ventricular enlargement.Conclusion T2DM,age and LADET are the independent risk factors for left ventricular enlargement.
出处
《江苏医药》
CAS
CSCD
北大核心
2012年第22期2668-2670,共3页
Jiangsu Medical Journal
基金
江苏高校优势学科建设工程项目(Jx10231081)
关键词
左心室扩大
Left ventricular enlargement
