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肩袖损伤脂肪浸润研究进展 被引量:6

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摘要 长期随访研究发现肩袖损伤修复术后有较高复发率,而脂肪浸润参与相关病理发展进程,并可能是手术失败或预后不良的重要原因之一。动物模型研究和临床研究均发现肩袖损伤,尤其是慢性肩袖损伤或巨大肩袖损伤发病过程中更易出现脂肪浸润和肌肉萎缩,这种病理改变并不因为手术干预而中止。有研究表明Wnt信号通路及转录因子PPAR和C/EBPβ等参与脂肪细胞生成和转化。寻找肩袖损伤患者脂肪浸润易发因素等已成为近年研究热点。
出处 《国际骨科学杂志》 2012年第6期366-367,371,共3页 International Journal of Orthopaedics
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