摘要
目的探讨多潘立酮与黄芪注射液联合治疗糖尿病性胃轻瘫患者的临床效果。方法选择糖尿病性胃轻瘫患者60例,在控制血糖基础上给予多潘立酮和黄芪注射液联合治疗。治疗前后进行胃电图及24 h动态心电图检查;对本组患者治疗前后主要临床症状进行评分。结果 60例糖尿病性胃轻瘫患者治疗后胃电图胃电主频率比和胃电主功率比显著高于治疗前,差异有统计学意义(P<0.05);治疗后SDNN、SDANN、SDNNindex、rMSSD、LF、HF、LF/HF分别与治疗前比较,差异有统计学意义(P<0.05);治疗后症状评分与治疗前比较,差异有统计学意义(P<0.05)。结论多潘立酮联合黄芪注射液治疗能够改善糖尿病性胃轻瘫患者胃动力,改善交感和迷走神经平衡失调,治疗效果显著。
Objective To investigate the clinical effect of Domperidone combined with Astragalus injection in the treatment of diabetic gastroparesis. Methods Chosed 60 cases of diabetic gastroparesis patients, and then gave them Domperidone and Astragalus combination therapy on the basis that the blood sugar had been controlled. Did EGG and 24-hour dynamic ECG examination and scored the main clinical symptoms in this group of patients before and after the therapy. Results In this group of patient after therapy,the main frequency ratio and main power ratio of the gastric electrical on EGG were sig- nificantly higher than those before treatment, the differences were statistically significant （P 〈 0.05）; Respectively com- pared the SDNN, SDANN SDNNindex,rMSSD, LF, HF, LF/HF after therapy to those before therapy, the differences were statistically significant （P 〈 0.05）; compared the symptoms after therapy to those beforetherapy,the differences were statis- tically significant（P 〈 0.05）. Conclusion Domperidone and Astragalus injection combination therapy not only can improve the gastric motility of the diabetic gastroparesis patients,but also can improve the sympathetic and vagus nerve imbalance, and the treatment effect is remarkable.
出处
《中国现代医生》
2012年第32期63-64,共2页
China Modern Doctor
