摘要
目的:优选附子的高压蒸制工艺。方法:以双酯型生物碱含量、总生物碱含量及外观质量为综合评价指标,对高压蒸制时间、压力及软化方式3个因素进行考察,采用L9(34)正交试验法优选附子的高压蒸制工艺。结果:附子最佳高压蒸制工艺为A2B2C2,即附子经润湿法处理后,0.10 MPa压力下蒸制150 min。结论:该优选的工艺简便、易行、可控,可作为代替附子传统炮制工艺的新方法。
Objective： To optimize high pressure steaming process of Aconitum carmichaelii. Method： Orthogonal test was used to optimize high pressure steaming process of A. carmichaelii with appearance quality, the content of diester diterpenoid alkaloids and total alkaloid as comprehensive evaluation index, high pressure steaming time, pressure and softening way were selected as factors. Result： Optimum high pressure steaming technology was A2B2C2, that of treated by wetting method, steamed 150 min at 0. 10 MPa. Conclusion： This optimized process was simple, practical and easy to control, it could be used as a new method to replace traditional processing technology of A. carmichaelii.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第23期20-24,共5页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广东省科技厅课题(2009B030801300)
关键词
附子
高压蒸制
正交设计
双酯型生物碱
单酯型生物碱
总生物碱
Aconitum carmichaelii
high pressure steaming
orthogonal design
diester diterpenoid alkaloids
monoester alkaloid
total alkaloid
