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左氧氟沙星三联疗法根除幽门螺杆菌32例临床观察 被引量:1

Evofloxacin triple therapy for eradication of Helicobacter pylori clinical observation of 32 cases
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摘要 目的:观察左氧氟沙星、兰索拉唑、阿莫西林三联疗法根除幽门螺杆菌(Hp)的临床疗效。方法:回顾性分析我院2009年2月-2012年2月收治的32例幽门螺杆菌感染(Hp阳性)患者的临床资料,随机均分为治疗组(16例)和观察组(16例),治疗组采用左氧氟沙星+兰索拉唑+阿莫西林三联疗法。观察组采用奥美拉唑+铋剂+阿莫西林+甲硝唑四联疗法,观察比较两组疗效。结果:治疗组对再次治疗病例Hp根除率为93.75%,观察组为87.5%,两组根除Hp比较无统计学意义(P〉0.05)。结论:左氧氟沙星+兰索拉唑+阿莫西林三联疗法对Hp治疗失败后的Hp根除率与以铋剂为基础加质子泵抑制剂(PPI)的四联疗法对Hp的根除率接近,但用药简单,患者容易接受。 Objective:o observe the effect of lansoprazole, amoxicillin, levofloxaein triple therapy for eradication of Hellcobacter pylori ( Hp ) clinical efficacy. Methods:Retrospective analysis of our hospital in 2009 February - 2012 February treated 32 cases of infection of Helicobacter pylori ( Hp+)in patients with clinical data, were randomly divided into treatment group ( 16 cases) and observation group(n=16), treated with levo- floxaein amoxicillin+lansoprazole+ triple therapy. The observation group was treated with omeprazole and amoxicillin and metronidazole in bismuth quadruple therapy, were compared between the two groups. Result: The treatment group treatment again case Hp eradication rate was 93.75 %, was 87. 5% in the observation group,two groups of eradication of Hp was not statistically significant (P〉0.05). Conclusion~ Levofloxacin amoxlcil- lin+lansoprazole+trlple therapy on Hp treatment after failure of eradication rate of Hp and to blsmuth--based plus proton pump inhibltors ( PPI ) quadruple therapy on Hp eradication rates close to, but.is easy to use, easy to be accepted by the patients.
作者 林上伟
出处 《按摩与康复医学》 2012年第33期151-151,共1页 Chinese Manipulation and Rehabilitation Medicine
关键词 幽门螺杆菌 感染 左氧氟沙星 治疗 观察 Helicobacter pylori Infection Levofloxacln Treatment Observation
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