摘要
[Objective] To establish good animal models of hepatocellular carcinoma （HCC） and serve treatment of HCC in humans. [Method] Several common animal models of HCC were introduced briefly. [Result] The commonly used animal models include C57BL/6J mouse model of or- thotopic HCC induced with Hepa1-6 cells, nude mouse model of HCC constructed with Hep_G2 cell lines, rat HCC model constructed through direct transplantation or direct injection, HU-PBL-SCID mice modal, and other transplanted HCC models or genetic HCC models. [ Conclusion] Animal model is an important means and platform for experimental studies. To establish animal models of HCC is of important significance for studies on pathogenesis, diagnosis and treatment of HCC.
[Objective] To establish good animal models of hepatocellular carcinoma （HCC） and serve treatment of HCC in humans. [Method] Several common animal models of HCC were introduced briefly. [Result] The commonly used animal models include C57BL/6J mouse model of or- thotopic HCC induced with Hepa1-6 cells, nude mouse model of HCC constructed with Hep_G2 cell lines, rat HCC model constructed through direct transplantation or direct injection, HU-PBL-SCID mice modal, and other transplanted HCC models or genetic HCC models. [ Conclusion] Animal model is an important means and platform for experimental studies. To establish animal models of HCC is of important significance for studies on pathogenesis, diagnosis and treatment of HCC.
