摘要
目的:研究异丙酚在新生儿全凭麻醉中应用的可行性。方法:对本院收治的58例新生儿患儿实施开腹手术,将全部患儿随机均分为两组,对照组采取羟丁酸钠静脉麻醉,观察组采取异丙酚全凭静脉麻醉,对比两组麻醉前后患儿的体征变化情况,同时统计呼吸抑制与拔管时间。结果:麻醉后观察组收缩压显著低于对照组(P<0.01),气管导管拔除后5min不给面罩吸氧时观察组血氧保和度明显高于对照组(P<0.05),观察组呼吸抑制发生率明显高于对照组(P<0.05),观察组拔管时间显著少于对照组(P<0.01)。结论:异丙酚应用于新生儿全静脉麻醉中是安全可行的,但应在手术过程中严密监测患者的体征变化情况,积极预防或及时处理呼吸抑制。
Objective：To study the feasibility of propofol application in neonatal TIVA.Methods：58 cases of newborn children admitted to our hospital were treated with laparotomy surgery,all the children were randomly and average divided into two groups,the control group was given sodium oxybate intravenous anesthesia,the observation group was given propofol TIVA,the situation of signs of change of two groups children before and after anesthesia,and at the same time respiratory depression and extubation time was counted.Results： Systolic blood pressure of the observation group was significantly lower than the control group after anesthesia（P0.01）,the degree of oximeter paul of the observation group was significantly higher than the control group（P0.05） when 5min after tracheal extubation and not give the oxygen mask,the rate of respiratory depression of the observation group was significantly higher than that in control group（P0.05）,extubation time of the observation group was significantly less than that of the control group（P0.01）.Conclusion：The propofol in neonatal total intravenous anesthesia is safe and feasible,but should be closely monitored during surgery signs of change of the patient’s situation,actively preven or timely process respiratory depression.
出处
《中国医药导刊》
2012年第10期1800-1801,共2页
Chinese Journal of Medicinal Guide
