摘要
目的:系统评价硝酸钾牙膏抗牙本质敏感的效果。方法:采用Cochrane系统评价的方法,检索1966～2010年间评价硝酸钾抗敏感牙膏效果的随机对照研究,采用RevMan 5.1.1软件进行敏感结果的Meta分析。结果:检索到265篇相关文献,最终纳入8篇(共501例)。5%硝酸钾组4周冷空气刺激VAS指标优于对照组(WMD:-0.98,95%CI:-1.17～-0.80);4、8周吹气敏感指标优于对照组(SMD:-1.23,95%CI:-1.82～-0.64;SMD:-1.07,95%CI:-1.36～-0.79);4、8周探诊敏感指标优于对照组(WMD:7.49,95%CI:5.90～9.07;WMD:10.06,95%CI:8.23～-11.88)。结论:已有的证据支持硝酸钾牙膏的抗敏感效果。
Objective：To evaluate the desensitizing efficacy of potassium nitrate toothpaste on dentine. Methods： The related studies from 1966 to 2010 were searched and screened by Cochrane reviewer＇s handbook. Four reviewers extracted the data and assessed the quality of studies independently using a specially designed form. The statistical analysis was performed by RevMan 5.1.1 software. Re- sults： 8 studies （including 501 subjects） were included in the meta-analysis which showed the superior effect of potassium nitrate toothpaste on air blast sensitivity at 4 and 8 week follow up （ SMD ： - 1.23, 95% CI ： - 1.82 ~ - 0.64 and SMD ： - 1.07, 95% CI ： -1.36 N - 0.79, respectively）, visual analog scale to cold air blast stimuli at 4 week （WMD： -0.98, 95% CI： - 1. 17 -0.80）, and tactile sensitivity at4 and 8 week （WMD： 7.49, 95% CI： 5.90 N9.07 and WMD： 10.06, 95% CI： 8.23 - -11.88, respectively）. Condusion： The available evidence supports the desensitizing efficacy of potassium nitrate toothpaste.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2012年第6期721-726,共6页
Journal of Practical Stomatology
关键词
牙本质敏感
硝酸钾
系统评价
随机对照试验
牙膏
Dentine hypersensitivity
Potassium nitrate
Systematic review
Clinical trial
Toothpaste
