期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

格列美脲联合预混胰岛素治疗2型糖尿病疗效观察 被引量：2

下载PDF
导出
摘要 在、2型糖尿病治疗中，预混胰岛素与口服降糖药有诸多的联合方案，与增敏剂、双胍类药物、α-糖苷酶抑制剂联用已被广泛认同；但磺脲类药物与预混胰岛素联用因疗效及低血糖风险等方面的原因而在学术界存有争议。我们对此进行了观察，现将结果报道如下。
作者 罗蕴之 王燕
机构地区 新疆自治区人民医院内分泌科
出处 《临床荟萃》 CAS 2012年第23期2090-2091,共2页 Clinical Focus
关键词 糖尿病 2型 磺酰脲化合物 胰岛素
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献7

  • 1Garber AJ. Benefits of combination therapy of insulin and oral hypoglycemic agents [ J ]. Arch Intern Med, 2003, 163 ( 15 ) : 1781-1782.
  • 2No authors listed. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes[J]. Lancet, 1998,352 (9131) 837-853.
  • 3U KPDS group. Association of glycaemia with macrovascular and microvaseular complications of type 2 diabetes (UKPDS 35): aprospective observational study [J]. BMJ, 2000, 321 ( 7258 ) : 405-412.
  • 4Goff DC Jr,Bigger JT,Buse JB,et al. Effects of intensive glucose lowering in type 2 diabetes[J]. N Engl J Med, 2008,358 (24): 2545-2559.
  • 5王佳,邹大进.2型糖尿病治疗新动向——高质量控制血糖的六大要点[J].中国实用内科杂志,2009,29(5):413-416. 被引量：20
  • 6Gentile S, Turco S, Guarino G, et al. Effect of treatment with acarbose and insulin in patients with non-insulin-dependent diabetes mellitus associated with non-alcoholic liver cirrhosis [J].Diabetes Obes Metab,2001,3(1)33-40.
  • 7Steil GM, Rebrin K, Mastrototaro J, et al. Determination of plasma glucose during rapid glucose excursion with a subcutaneous glucose sensor[J]. Diabetes Teehnol Ther, 2003,5 (1) :27-31.

二级参考文献9

  • 1Meugnier E, Faraj M, Rome S, et al. Acute hyperglycaemia induces a global downregulation of gene expression in adipose tissue and skeletal muscle of healthy subjects[J]. Diabetes,2007,56:992 - 999.
  • 2Abraira C, Duekworth WC, Moritz T. Glycaemic separation and risk factor control in the Veterans Affairs Diabetes Trial:an interim report [ J ]. Diabetes Obes Metab,2008:129 [ Epub ahead of print ].
  • 3Utzschneider KM, Prigeon RL, Carr DB, et al. Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responses [ J ]. Diabetes Care ,2006,29 (2) : 356 - 362.
  • 4Holman RR, Paul SK, Bethel MA, et al. 10-year follow-up of intensive glucose control in type 2 diabetes [ J ]. N Engl J Med,2008, 359( 15 ) : 1577 - 1589.
  • 5Jianping Weng, Yanbing Li, Wen Xu, et al. Effect of intensive insulin therapy on B-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial [ J ]. Lancet,2008,371 ( 9626 ) : 1577 - 1580.
  • 6Meerwaldt R, Lutgers HL, Links TP, et al. Skin autofluorescence is a strong predictor of cardiac mortality in diabetes. Diabetes Care, 2007,30 ( 1 ) : 107 - 112.
  • 7Madala MC, Franklin BA, Chen AY, et al. Obesity and age of first non-ST-segment elevation myocardial infarction [ J ]. J Am Coll Cardiol,2008,52 ( 12 ) :979 - 985.
  • 8Batsis JA ,Sarr MG, Collazo-Clavell ML, et al. Cardiovascular risk after bariatric surgery for obesity [ J ]. Am J Cardiol, 2008,102 (7) :930 -937.
  • 9Guangwei Li, Ping Zhang, Jinping Wang, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study [ J ]. Lancet, 2008,371 (9626) : 1783 - 1789.

共引文献19

同被引文献22

  • 1Standl E,Janka HU.High serum insulin conceratrations in relation toother cardiovascular risk factors in macrovasculag disease of type 2 diabetes[J].Horm M etab Res,1985,15(Suppl):46-51.
  • 2Martin DB.Atherogenicity of insulin[J].Diabetes Res Clin Pratt,1988,4(Suppl):58,61.
  • 3Feldman JM,Lebovitz HE.Appraisal of the extrapancreatic actions of sulfonylurcas[J].Arch Intem M ed,1969,123:314-322.
  • 4Muller G,Satoh Y,Geisen K.Extrapancrcatic effects of sulphonylureas a comparison betw een glimepiride and conventional sulphonylureas[J].Diabetes Res Clin Pract,1995,28(Suppl):S115-S137.
  • 5Johnson JL,Wolf SL,Kabadi UM.Efficacy of insulin and sulfonylurea combination therapy in type 2 diabetes:A meta-analysis of the randomized placebo-controlled trims[J].Arch Intern M ed,1996,156:259-264.
  • 6Strowig SM,Pe-santa ML,Raskin P,et al.Comparison of insulin monotherapy and combination therapy w ith insulin and mefformin or insulin and troglimzone in type 2 diabetes[J].Diabetes Care,2002,25:2133-2140.
  • 7Hatao K,Kaku K,Matsuda M,et al.Sulfonylurea stimulates liverfructoso-2,6-bisphosphate formation in proportion to its hypoglycemicaction[J].Diabetes Res Clin Pract,1985,1:49-53.
  • 8Mori RC,Hirabaga SM,Hiram AE,et al.Glimepiride as insulin sensitizer:increased liver and muacle responses to insulin[J].Diabetes Obes Metab,2005,10(7):596-600.
  • 9韩春生.甘精胰岛素和诺和灵N分别与格列美脲联合治疗2型糖尿病疗效比较[J].中国实用医药,2008,3(12):80-83. 被引量：32
  • 10李强.肥胖2型糖尿病的降糖新药及其临床应用[J].药品评价,2012(16):23-27. 被引量：3

引证文献2

二级引证文献17

临床荟萃
2012年 第23期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部