摘要
目的分析广西河池市第三人民医院2008～2011年白色念珠菌耐药性变化趋势,指导临床合理使用抗菌药物。方法回顾性调查该院2008年1月至2011年12月从临床分离的1 022株白色念珠菌,对8种常用抗真菌药物的耐药结果进行统计分析。结果该菌连续4年对两性霉素B的耐药率最低,为7.09%～8.80%,耐药率最高的为伊曲康唑,连续4年均大于80.00%。结论白色念珠菌对常用抗真菌药物都产生一定的耐药性,故应对送检标本及早进行真菌培养和药敏试验;为了减少多重耐药和深部真菌感染的发生,应合理使用抗菌药物和抗真菌药物。
Objective To analyse candida albicans resistance change trend for guiding clinical rational use of antimicrobiat agents from 200 to 2011Methods A retrospective survey in our hospital from January 2008 to Decem her 2011 from clinical 1022 strains separated candida albicans, drug resistances of 8 antibacterials were statistically analyaed. Results The bacteria for four consecutive years amphoteriein B in both the lowest rates were 7.09% -- 8.80 %. The highest drug resistance of this bacteria was lineaolid itraconazole, four consecutive annual average rates were more than 80.00 %. Conclusion Candida albicans antifungal can have resistance to common drugs commonly, so as to send the specimens fungi susceptibility test and training. In order to reduce multiple resistance and deep fungus infection occurrence, antibiotics and antifungal drugs should be used reasonably.
出处
《检验医学与临床》
CAS
2012年第23期2945-2946,共2页
Laboratory Medicine and Clinic
