摘要
目的:对比中医药序贯治疗模式和巩固治疗模式对Ⅲ/Ⅳ期胃癌患者总生存(OS)和中位生存期(MST)的影响。方法:选择2010年3月～2012年3月我院收治的60例Ⅲ/Ⅳ期胃癌患者。按照治疗方式的不同分为序贯组和巩固组。序贯组25例,采用中医药序贯模式治疗。巩固组35例,采用中医药巩固模式治疗。对比两组患者治疗后的生存情况。结果:60例患者的中位OS为16个月,序贯组的中位OS为33.0个月明显高于巩固组的20个月(P<0.05),服用中药汤剂患者的中位OS为23.8个月明显长于未服患者的15.6个月(P<0.05)。经分层统计,序贯组的MST(16.4个月)明显长于巩固组(7.3个月),P<0.05差异具有统计学意义。结论:中西医综合治疗Ⅲ/Ⅳ期胃癌能有效延长患者生存期,中医药序贯模式在延长患者生存期方面明显优于巩固治疗模式。
Objective：Compared the impactions of the TCM sequential mode and consolidation therapy mode against overall survival（OS） and median survival time（MST） of Ⅲ/Ⅳ gastric cancer patients.Methods：Our hospital from March 2010 to March 2012,60 cases of stage Ⅲ/Ⅳ gastric cancer patients were chosen.According to the different treatment modality were divided into the sequential group and consolidate group.Sequential group of 25 cases were given the TCM sequential mode treatment.Consolidate group of 35 patients were given the TCM consolidation therapy mode.Contrast the survival of the two groups of patients after treatment.Results：The median OS of 60 patients was 16.0 months,the median OS of the sequential group was 33.0 months was significantly higher than 20.0 months of consolidate group（P0.05）,median OS of patients taking TCM decoction was 23.8 months was significantly longer than 15.6 months of not serving the patients（P0.05）.Through stratified statistics,MST of the sequential group（16.4 months） was significantly longer than that of the consolidate group（7.3 months）,P0.05 statistically significant difference.Conclusion：The integrative medicine could effectively prolong the lifetime of the patients with Ⅲ/Ⅳ gastric cancer.The TCM sequential mode was significantly better than the TCM consolidation therapy mode in prolonging survival of patients.
出处
《中医临床研究》
2012年第21期62-63,共2页
Clinical Journal Of Chinese Medicine
关键词
中西医结合疗法
Ⅲ
Ⅳ期胃癌
序贯治疗
巩固治疗
Integrative therapy
Ⅲ/Ⅳ gastric
Sequential therapy
Consolidation therapy
